Department of Surgery, Hospital Clínico Universitario, Zaragoza, Spain.
Obes Surg. 2011 Feb;21(2):179-85. doi: 10.1007/s11695-010-0309-6.
There is a lack of long-term studies for metabolic syndrome after bariatric surgery. Our aim is to show the evolution of the parameters that define the metabolic syndrome after bariatric surgery, up to 10 years of follow-up, in order to clarify what technique gets better results with fewer complications.
The IDF definition of the metabolic syndrome was used for this study. One hundred twenty-five morbid obese and superobese patients underwent vertical banded gastroplasty. Two hundred sixty-five morbid obese and superobese patients had biliopancreatic diversion (Scopinaro and modified biliopancreatic diversions), and 152 morbid obese patients underwent laparoscopic gastric bypass. A mean follow-up of up to 7 years was done in all groups.
Prior to surgery, metabolic syndrome was diagnosed in 114 patients of Scopinaro group (76%), in 85 patients of modified biliopancreatic diversion group (73.9%), in 81 patients of laparoscopic gastric bypass (53.4%), and in 98 patients of vertical banded gastroplasty (78.4%). When metabolic syndrome parameters were evaluated at 7 years of follow-up, owing to weight gain, these results changed nearby to preoperative values in both laparoscopic gastric bypass and vertical banded gastroplasty groups.
According to our results, the best technique to resolve metabolic syndrome is the modified biliopancreatic diversion. Due to its high morbidity, it only must be considered in superobese patients. In obese patients, the laparoscopic gastric bypass may be a less agressive choice, but it should be coupled with lifestyle changes to keep away from the weight gain in the long run. Restrictive procedures may be indicated only in a few well-selected cases.
减重手术后代谢综合征的长期研究较少。我们的目的是展示减重手术后定义代谢综合征的参数的演变,随访时间长达 10 年,以明确哪种技术能获得更好的结果,同时并发症更少。
本研究采用 IDF 代谢综合征定义。125 例病态肥胖和超级肥胖患者接受垂直带胃成形术。265 例病态肥胖和超级肥胖患者行胆胰分流术(Scopinaro 和改良胆胰分流术),152 例病态肥胖患者行腹腔镜胃旁路术。所有组别的平均随访时间长达 7 年。
术前,Scopinaro 组 114 例(76%)、改良胆胰分流术组 85 例(73.9%)、腹腔镜胃旁路术组 81 例(53.4%)和垂直带胃成形术组 98 例(78.4%)诊断为代谢综合征。7 年随访时,由于体重增加,腹腔镜胃旁路术和垂直带胃成形术组的代谢综合征参数评估结果接近术前值。
根据我们的结果,解决代谢综合征的最佳技术是改良胆胰分流术。由于其高发病率,仅适用于超级肥胖患者。对于肥胖患者,腹腔镜胃旁路术可能是一种侵袭性较小的选择,但应结合生活方式改变,以避免长期体重增加。限制手术仅适用于少数精选病例。