Cazzo Everton, Callejas-Neto Francisco, Pareja José Carlos, Chaim Elinton Adami
Department of Surgery, Faculty of Medical Sciences, State University of Campinas (UNICAMP), R. Hermantino Coelho, 77/03-11, 13087-500, Campinas, Sao Paulo, Brazil,
Obes Surg. 2014 Jun;24(6):971-3. doi: 10.1007/s11695-014-1246-6.
Metabolic syndrome (MetS) is strongly linked to insulin resistance and has a high resolution rate after bariatric surgery. This study aims to determine whether post over preoperative ratios of surrogate insulin resistance markers (HOMA, TyG, and TG/HDL-c) are associated to postsurgical MetS reversal. This is a retrospective cohort study which involved 96 subjects with MetS who underwent Roux-en-Y gastric bypass (RYGB). Post over preoperative ratios of TyG and TG/HDL-c indexes were statistically associated to MetS resolution. The use of these ratios as a way to assess postsurgical insulin sensitivity response appears to be a simple and useful tool in clinical practice.
代谢综合征（MetS）与胰岛素抵抗密切相关，且在减肥手术后缓解率较高。本研究旨在确定替代胰岛素抵抗标志物（HOMA、TyG和TG/HDL-c）术后与术前的比值是否与术后代谢综合征的逆转相关。这是一项回顾性队列研究，纳入了96例行Roux-en-Y胃旁路术（RYGB）的代谢综合征患者。TyG和TG/HDL-c指数的术后与术前比值与代谢综合征的缓解在统计学上相关。在临床实践中，使用这些比值作为评估术后胰岛素敏感性反应的方法似乎是一种简单且有用的工具。
