Department of Oncology, Rambam Medical Center, Haifa, Israel.
J Appl Clin Med Phys. 2010 Jul 19;11(4):3244. doi: 10.1120/jacmp.v11i4.3244.
The design concept and dosimetric characteristics of a new applicator system for intraoperative radiation therapy (IORT) are presented in this work. A new hard-docking commercial system includes polymethylmethacrylate (PMMA) applicators with different diameters and applicator end angles and a set of secondary lead collimators. A telescopic device allows changing of source-to-surface distance (SSD). All measurements were performed for 6, 9, 12 and 18 MeV electron energies. Output factors and percentage depth doses (PDD) were measured in a water phantom using a plane-parallel ion chamber. Isodose contours and radiation leakage were measured using a solid water phantom and radiographic films. The dependence of PDD on SSD was checked for the applicators with the smallest and the biggest diameters. SSD dependence of the output factors was measured. Hardcopies of PDD and isodose contours were prepared to help the team during the procedure on deciding applicator size and energy to be chosen. Applicator output factors are a function of energy, applicator size and applicator type. Dependence of SSD correction factors on applicator size and applicator type was found to be weak. The same SSD correction will be applied for all applicators in use for each energy. The radiation leakage through the applicators is clinically acceptable. The applicator system enables effective collimation of electron beams for IORT. The data presented are sufficient for applicator, energy and monitor unit selection for IORT treatment of a patient.
本文介绍了一种用于术中放射治疗(IORT)的新型敷贴器系统的设计理念和剂量学特性。一个新的硬连接商业系统包括不同直径和敷贴器端角的聚甲基丙烯酸甲酯(PMMA)敷贴器以及一套次级铅准直器。一个伸缩装置允许改变源皮距(SSD)。所有测量均在水模体中进行,使用平面平行电离室测量输出因子和百分深度剂量(PDD)。使用固体水模体和射线照相胶片测量等剂量线轮廓和辐射泄漏。对于最小和最大直径的敷贴器,检查了 PDD 对 SSD 的依赖性。测量了输出因子对 SSD 的依赖性。制作 PDD 和等剂量线轮廓的硬拷贝,以帮助团队在手术过程中决定选择敷贴器的大小和能量。敷贴器输出因子是能量、敷贴器尺寸和敷贴器类型的函数。发现 SSD 校正因子对敷贴器尺寸和敷贴器类型的依赖性较弱。对于每种能量使用的所有敷贴器,将应用相同的 SSD 校正。敷贴器的辐射泄漏是临床可接受的。敷贴器系统能够有效地对电子束进行准直,用于 IORT。本文提供的数据足以用于 IORT 治疗患者的敷贴器、能量和监测器单位的选择。