无金属催化的砜腙与硫醇的还原偶联合成硫醚。
Synthesis of thioethers via metal-free reductive coupling of tosylhydrazones with thiols.
机构信息
College of Chemistry and Chemical Engineering, Jiangxi Normal University, 99 Ziyang Road, Nanchang, 330022, China.
出版信息
Org Biomol Chem. 2011 Feb 7;9(3):748-51. doi: 10.1039/c0ob00639d. Epub 2010 Nov 17.
PMID:21082133
Abstract
A metal-free procedure for the synthesis of thioethers is described via the base-promoted reductive coupling of tosylhydrazones with thiols through an insertion of a carbene into the S-H bond.
摘要
本文描述了一种通过碳烯插入 S-H 键，在碱性条件下促进砜腙与硫醇的还原偶联，从而实现硫醚合成的无金属方法。
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