Bernante Paolo, Francini Francesco, Zangrandi Fabio, Menegon Paola, Toniato Antonio, Feltracco Paolo, Pelizzo Maria Rosa
Department of Medical and Surgical Sciences, 3rd Clinic of General Surgery, University of Padua, Italy.
Obes Surg. 2003 Dec;13(6):951-3. doi: 10.1381/096089203322618858.
The intragastric balloon is filled with saline and methylene blue dye, to detect balloon deflation early and prevent bowel obstruction, by monitoring the patient's urine for changes in color.
An intragastric balloon filled with 590 ml of saline plus 10 ml of methylene blue was endoscopically placed under sedation in a 22-year-old man with morbid obesity (BMI 42 kg/m2). 3 days later, the patient's urine changed to dark green, and, suspecting a leaking balloon, endoscopy was repeated under sedation.
No signs of balloon deflation were seen, and the urine returned to normal color. The next day, the urine turned green again. 7 days later, the urine discoloration finally disappeared.
Propofol, a sedative commonly used by anesthesiologists during endoscopic procedures, is known to have several side-effects, and urine discoloration is one of them, albeit rare. This benign side-effect must be known to obesity surgeons to avoid pointless medical expenditure, unnecessary balloon removal and distress for patients and clinicians.
胃内球囊填充有生理盐水和亚甲蓝染料，通过监测患者尿液颜色变化来早期检测球囊放气并预防肠梗阻。
在镇静状态下，通过内镜将一个填充有590毫升生理盐水加10毫升亚甲蓝的胃内球囊置入一名22岁的病态肥胖男性（体重指数42千克/平方米）体内。3天后，患者尿液变为深绿色，怀疑球囊漏气，遂在镇静状态下再次进行内镜检查。
未发现球囊放气迹象，尿液颜色恢复正常。第二天，尿液再次变绿。7天后，尿液变色最终消失。
丙泊酚是麻醉医生在内镜检查过程中常用的镇静剂，已知有多种副作用，尿液变色是其中之一，尽管罕见。肥胖症外科医生必须了解这种良性副作用，以避免不必要的医疗费用、不必要的球囊移除以及给患者和临床医生带来困扰。
