Department of Respiratory Medicine, Sherwood Forest Hospitals NHS Foundation Trust, Mansfield Road, Sutton-in-Ashfield, Nottinghamshire.
Chron Respir Dis. 2010;7(4):239-45. doi: 10.1177/1479972310378311.
UK guidelines for domiciliary oxygen have suggested the six-minute walk test or shuttle walk tests as suitable functional measures for the clinical assessment of ambulatory oxygen (AO). To date, there is limited evidence that would support the use of shuttle walk tests as assessment tools for AO. The endurance shuttle walk test (ESWT) is used increasingly as an assessment tool within pulmonary rehabilitation (PR) but its potential as an investigative test for AO has not been explored. Using the same test for both PR and AO assessment is appealing since it would improve efficiency and act to standardise outcome measures in this patient population. The aim of this study was to examine the responsiveness and repeatability of the ESWT to AO and to compare the response with that of the six-minute walk test (6MWT). Twenty-three patients with chronic obstructive pulmonary disease (COPD) performed, in random order, the ESWT and the 6MWT on air and whilst breathing AO. Oxygen saturation and Borg ratings of breathlessness and perceived exertion were recorded. On a third day, eleven patients repeated the ESWT with AO in order to measure repeatability. There was a significantly greater change in the ESWT with oxygen than the change recorded from the 6MWT (66 [91] vs 6 [28] m respectively; P < .05). When repeated on a separate day, the mean difference (95% CI) between distances walked on the ESWT with AO was 0.91 (-47, 49) m. The ESWT was more responsive than the 6MWT for detecting improvements in walking endurance whilst breathing AO.
英国家庭氧疗指南建议采用 6 分钟步行试验或穿梭步行试验作为评估门诊氧疗（AO）的合适功能指标。迄今为止，支持使用穿梭步行试验作为 AO 评估工具的证据有限。耐力穿梭步行试验（ESWT）在肺康复（PR）中越来越多地被用作评估工具，但它作为 AO 调查性测试的潜力尚未得到探索。在 PR 和 AO 评估中使用相同的测试具有吸引力，因为它可以提高效率并使该患者群体的结果测量标准化。本研究旨在检验 ESWT 对 AO 的反应性和可重复性，并比较其与 6 分钟步行试验（6MWT）的反应。23 例慢性阻塞性肺疾病（COPD）患者依次在空气和 AO 下进行 ESWT 和 6MWT。记录氧饱和度和呼吸困难 Borg 评分以及感知用力程度。在第三天，11 例患者重复 AO 下的 ESWT 以测量可重复性。与 6MWT 记录的变化相比，ESWT 随氧气的变化明显更大（分别为 66 [91] 与 6 [28] m；P <.05）。在另一天重复进行时，ESWT 与 AO 行走距离的平均差异（95%CI）为 0.91（-47，49）m。与 6MWT 相比，ESWT 更能检测到 AO 呼吸时步行耐力的改善。
