[Quantitative analysis of the immunogenic activity of SV40 virus and the cells of tumors induced by this virus].

The study of specific antitumour immunity induced by onogenic SV40 virus and by cell of SV40 virus and by cells of SV40-induced tumour of Syrian hamster demonstrated direct correlation between the level of specific antitumour resistance and the immunizing virus and tumour cell doses. The minimal resistance-inducing dose of the wild type SV40 virus strain was 10 times higher than that of ts A-30 mutant of this virus. Minimal resistance-inducing dose of irradiated cells of the tumour was about 9 x 10(5) cells; a 10-fold increase of this dose significantly increased the specific antitumour immunity level.