南五味子中的三萜类化合物——南五味子内酯A-J

Kadcoccilactones A-J, triterpenoids from Kadsura coccinea.

作者信息

Gao Xue-Mei, Pu Jian-Xin, Huang Sheng-Xiong, Lu Yang, Lou Li-Guang, Li Rong-Tao, Xiao Wei-Lie, Chang Ying, Sun Han-Dong

机构信息

State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, Yunnan, People's Republic of China.

出版信息

J Nat Prod. 2008 Jul;71(7):1182-8. doi: 10.1021/np800078x. Epub 2008 Jul 1.

DOI:10.1021/np800078x

PMID:18590312

Abstract

Ten new highly oxygenated triterpenoids, kadcoccilactones A-J (1-10), and two known triterpenoids, kadsuphilactone A and micrandilactone B, were isolated from the stems of the evergreen climbing plant Kadsura coccinea. The structures of the new compounds were elucidated by spectroscopic evidence, with that of 1 confirmed by single-crystal X-ray diffraction analysis. This is the first report on nortriterpenoids (2, 4-6, 8-10) from the genus Kadsura.

摘要

从常绿攀援植物绯红南五味子的茎中分离得到10个新的高度氧化三萜类化合物，南五味子内酯A-J（1-10），以及2个已知的三萜类化合物，南五味子内酯A和小花五味子内酯B。通过光谱数据解析了新化合物的结构，其中化合物1的结构经单晶X射线衍射分析得以确证。这是关于南五味子属降三萜类化合物（2, 4-6, 8-10）的首次报道。