Digestive Endoscopy Unit, Catholic University, Largo Francesco Vito 1, Rome, Italy.
Dig Liver Dis. 2011 Apr;43(4):300-4. doi: 10.1016/j.dld.2010.10.005. Epub 2010 Nov 18.
Colon capsule endoscopy (CCE) represents a new diagnostic, endoscopic technology for colonic exploration. Current protocols of preparation led to discordant rates of adequate cleansing level or CCE excretion.
To evaluate the effect of a new regimen of bowel preparation for CCE on colon cleansing levels and on rate of capsule excretion.
60 patients were prospectively enrolled. The new regimen of preparation consisted of a split regimen of PEG administration and of a 45 mL dose of sodium phosphate (NaP). Four senna tablets and a low-residue diet were also included. CCE excretion rate, colon cleansing, and accuracy were assessed.
Forty-six patients were included in the final analysis, 13 patients (22%) being excluded because of preparation protocol deviations and one due to CCE technical failure (2%). At CCE, bowel preparation was rated as good in 78% of patients, fair in 20% and poor in 2%. CCE excretion rate occurred in 83% of patients. CCE sensitivity and specificity for significant findings was 100% and 95%, respectively.
The combination of a split-dose of PEG solution with a low dose of NaP boosters resulted in high rates of adequate cleansing level and CCE excretion.
结肠胶囊内镜（CCE）是一种用于结肠检查的新的诊断性内镜技术。目前的准备方案导致了不同的清洁程度或 CCE 排泄率。
评估一种新的 CCE 肠道准备方案对结肠清洁程度和胶囊排泄率的影响。
60 例患者前瞻性入组。新的准备方案包括 PEG 分剂量给药和 45 毫升剂量的磷酸钠（NaP）。还包括 4 片番泻叶和低残留饮食。评估 CCE 排泄率、结肠清洁度和准确性。
46 例患者纳入最终分析，13 例（22%）因准备方案偏差和 1 例（2%）因 CCE 技术失败而被排除。在 CCE 检查中，78%的患者肠道准备良好，20%的患者肠道准备良好，2%的患者肠道准备较差。83%的患者进行了 CCE 排泄。CE 对有意义发现的敏感性和特异性分别为 100%和 95%。
PEG 溶液分剂量与低剂量 NaP 联合使用可达到较高的清洁水平和 CCE 排泄率。
