Department of Urology, Cork University Hospital, Wilton, Co. Cork, Republic of Ireland.
Ir J Med Sci. 2011 Mar;180(1):109-14. doi: 10.1007/s11845-010-0643-7. Epub 2010 Nov 19.
Traditionally, the incidence of testicular cancer (TCa) has shown a remarkable geographical variation.
To examine whether the rates of TCa varied within Ireland itself and to find possible explanations for any observations made.
We observed the incidence of TCa in counties in Ireland between January 1994 and December 2007. The rate of cryptorchidism over the same time was calculated. Incidence of TCa by socio-economic status was reviewed. The role of environmental pollutants was explored. We analysed teenage obesity data as a risk factor for the development of TCa in adulthood.
Cork had a significantly higher rate of TCa than any other county in Ireland. Cork also had high rates of cryptorchidism, but interestingly not the highest nationwide. In Cork County specifically, least deprived areas had significantly higher rates of TCa. Organic pollutants previously linked to the development of TCa have been identified in large industries located only in Cork. Teenage obesity rates in Cork were not higher than elsewhere.
There is a higher incidence rate of TCa in Cork than any other county. High rates of cryptorchidism alone cannot explain this. There appears to be a link with higher socio-economic status and possibly industrial pollutants. The association between sedentary lifestyle and the development of TCa is unproven.
传统上，睾丸癌（TCa）的发病率表现出显著的地域差异。
检查爱尔兰国内 TCa 的发病率是否存在差异，并寻找任何观察结果的可能解释。
我们观察了 1994 年 1 月至 2007 年 12 月期间爱尔兰各郡的 TCa 发病率。同时计算了同期隐睾的发病率。还回顾了 TCa 按社会经济地位的发病率。探讨了环境污染物的作用。我们分析了青少年肥胖数据，作为成年后患 TCa 的风险因素。
科克郡的 TCa 发病率明显高于爱尔兰其他任何郡。科克郡的隐睾发病率也很高，但有趣的是，其发病率并非全国最高。在科克郡，最贫困地区的 TCa 发病率明显更高。先前与 TCa 发展相关的有机污染物已在仅位于科克的大型工业企业中被发现。科克的青少年肥胖率并不高于其他地区。
科克的 TCa 发病率高于爱尔兰其他任何郡。单纯高隐睾率无法解释这一点。与较高的社会经济地位和可能的工业污染物之间似乎存在关联。与久坐的生活方式与 TCa 发展之间的关联尚未得到证实。
