Lai Mao-Hua, Ma Hong-Xia, Yao Hong, Liu Hua, Song Xing-Hua, Huang Wan-Yi, Wu Xiao-Ke
The First Affiliated Hospital of Guangzhou Medical College, Guangzhou 510120, China.
Zhen Ci Yan Jiu. 2010 Aug;35(4):298-302.
To observe the effect of abdominal acupuncture on the endocrine and metabolic level in obesity-type polycystic ovarian syndrome (PCOS) patients.
Eighty-six PCOS patients were randomly and equally divided into medication group and abdominal acupuncture group. Patients of medication group were treated with metformin (250 mg/time, t.i. d. in the 1st week, and 500 mg/time, t.i.d. thereafter) for 6 months,and those of abdominal acupuncture group were treated by abdominal acupuncture [Zhongwan (CV 12), Liangmen (ST 21), etc., once daily for 6 months]. Changes of the body height, body Mass index (BMI), waist-hip ratio (WHR), Ferriman-Galleey score (FGS), menstrual frequency (MF) and ovarian volume (OV) were determined. Serum luteotrophic hormone (LH), free testosterone (T), follicle-stimulating hormone (FSH) contents were detected with radioimmunoassay. Fasting blood glucose (FBG), fasting insulin (FIN), total cholesterol (TC), triglyceride (TG), low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), Homa insulin resistance index (IRI) were detected with chromatometry respectively.
After the treatment, BMI, WHR, FGS and OV were reduced significantly in both medication and abdominal acupuncture groups (P < 0.05), while MF of the two groups increased evidently (P < 0.05), and the effects of abdominal acupuncture group were significantly superior to those of medication group in down-regulating BMI, WHR and upregulating MF (P < 0.05). Regarding the reproductive hormons, serum LH, LH/FSH and T levels in the two groups decreased significantly (P< 0.05), and the effect of abdominal acupuncture was superior to that of medication group in reducing serum T level (P < 0.05). Following the treatment, FBG, BG and FIN and INS contents 2 h after meal,and Homa IR in both medication and abdominal acupuncture groups all decreased considerably (P < 0.05), but without significant differences between them (P > 0.05). Regarding the blood lipid levels after the treatment, serum TC, TG, and LDL-C levels of the two groups decreased significantly (P < 0.05), while serum HDL-C level increased remarkably (P<0.05), without significant differences between the two groups in these indexes (P > 0.05).
Abdominal acupuncture treatment can improve the endocrine and metabolic function of patients with obesity-type PCOS.
观察腹针疗法对肥胖型多囊卵巢综合征（PCOS）患者内分泌及代谢水平的影响。
将86例PCOS患者随机等分为药物治疗组和腹针治疗组。药物治疗组患者服用二甲双胍（第1周250mg/次，每日3次，之后500mg/次，每日3次），疗程6个月；腹针治疗组患者采用腹针疗法[针刺中脘（CV 12）、梁门（ST 21）等穴位，每日1次，疗程6个月]。测定两组患者身高、体重指数（BMI）、腰臀比（WHR）、费里曼-加利评分（FGS）、月经频率（MF）及卵巢体积（OV）的变化。采用放射免疫法检测血清促黄体生成素（LH）、游离睾酮（T）、促卵泡生成素（FSH）含量。分别采用比色法检测空腹血糖（FBG）、空腹胰岛素（FIN）、总胆固醇（TC）、甘油三酯（TG）、低密度脂蛋白胆固醇（LDL-C）、高密度脂蛋白胆固醇（HDL-C）、胰岛素抵抗指数（Homa-IRI）。
治疗后，药物治疗组和腹针治疗组的BMI、WHR、FGS及OV均显著降低（P<0.05），两组MF均明显升高（P<0.05），腹针治疗组在降低BMI、WHR及升高MF方面的效果显著优于药物治疗组（P<0.05）。在生殖激素方面，两组血清LH、LH/FSH及T水平均显著降低（P<0.05），腹针治疗组在降低血清T水平方面的效果优于药物治疗组（P<0.05）。治疗后，药物治疗组和腹针治疗组的FBG、餐后2小时血糖及FIN、胰岛素含量以及Homa-IR均显著降低（P<0.05），但两组间差异无统计学意义（P>0.05）。在血脂水平方面，治疗后两组血清TC、TG及LDL-C水平均显著降低（P<0.05），血清HDL-C水平显著升高（P<0.05），两组间这些指标差异无统计学意义（P>0.05）。
腹针疗法可改善肥胖型PCOS患者的内分泌及代谢功能。
