Department of Pathology and Laboratory Medicine, Taipei Veterans General Hospital, and Department of Pathology, National Yang-Ming University School of Medicine, Taipei, Taiwan, ROC.
J Chin Med Assoc. 2010 Nov;73(11):602-4. doi: 10.1016/S1726-4901(10)70131-3.
Phyllodes tumor (PT) consists of stroma of variable grading and benign ductal epithelium. Although exceptional, carcinomas that arise from the epithelium in PTs do exist, and seem to behave less aggressively than the usually encountered breast carcinoma. To the best of our knowledge, among the invasive carcinomas that have arisen in PTs, only 1 has been proved to have metastatic carcinoma in the lymph nodes. Here, we describe the youngest woman to have invasive ductal carcinoma that arose in a borderline PT, with isolated carcinoma cells in the sentinel lymph node. Whether such a combined lesion carries a more indolent course is also discussed.
叶状肿瘤（PT）由不同分级的间质和良性导管上皮组成。虽然罕见，但确实存在起源于 PT 上皮的癌，其行为似乎不如通常遇到的乳腺癌活跃。据我们所知，在起源于 PT 的浸润性癌中，只有 1 例被证实有淋巴结转移癌。在这里，我们描述了一位最年轻的女性，她患有在交界性叶状肿瘤中发生的浸润性导管癌，前哨淋巴结中存在孤立的癌细胞。这种联合病变是否具有更惰性的病程也在讨论中。
