使用数字成像和通信在医学（DICOM）数据和供应商独立的斑点跟踪软件评估儿童的心肌变形。
Assessment of myocardial deformation in children using Digital Imaging and Communications in Medicine (DICOM) data and vendor independent speckle tracking software.
机构信息
Division of Cardiology, Labatt Family Heart Center, Hospital for Sick Children and University of Toronto, Toronto, Ontario, Canada.
出版信息
J Am Soc Echocardiogr. 2011 Jan;24(1):37-44. doi: 10.1016/j.echo.2010.09.018. Epub 2010 Nov 20.
BACKGROUND
Analysis of myocardial deformation from data stored in Digital Imaging and Communications in Medicine format using vendor-independent software may be useful for clinical and research purposes but has not been evaluated in children.
METHODS
Grayscale images were prospectively acquired on Vivid 7 (GE Healthcare) and iE33 (Philips Medical Systems) ultrasound systems in 49 children. Digital Imaging and Communications in Medicine and raw data were analyzed using vendor-independent software (Cardiac Performance Analysis, Tomtec Imaging Systems) and vendor-specific software (EchoPAC and QLAB) and results compared. In addition, vendor-independent software using images at 30 frames/sec were compared with images at the higher acquisition frame rate.
RESULTS
Measurement of short-axis radial and circumferential strain (ε) and apical four-chamber longitudinal ε by vendor-independent software was possible in >92% of the children. Intraobserver and interobserver coefficients of variation for global circumferential and longitudinal ε ranged from 7.1% to 15.3% and for radial ε from 23.9% to 30.2%. Strain values were somewhat higher when using GE images at acquisition frame rates compared with ε values using GE images stored at 30 frames/sec. Strain values obtained by vendor-independent software were comparable with those obtained by vendor-specific software for longitudinal ε and higher for circumferential ε. Radial ε values obtained by vendor-independent software were lower than ε values by EchoPAC and higher than ε values by QLAB.
CONCLUSIONS
Vendor-independent software-derived ε is feasible and potentially valuable for measuring myocardial deformation in research and in multicenter studies using images from different ultrasound systems, especially for longitudinal deformation. However, a systematic bias for circumferential ε and a high variability in radial ε measurements remain concerns.
背景
使用与供应商无关的软件分析以数字成像和通信在医学格式中存储的数据的心肌变形可能对临床和研究目的有用，但尚未在儿童中进行评估。
方法
在 Vivid 7（GE Healthcare）和 iE33（飞利浦医疗系统）超声系统上对 49 名儿童进行前瞻性灰阶图像采集。使用与供应商无关的软件（心脏性能分析，Tomtec 成像系统）和供应商特定的软件（EchoPAC 和 QLAB）分析数字成像和通信在医学格式和原始数据，并比较结果。此外，还比较了使用 30 帧/秒图像的与供应商无关的软件与更高采集帧率的图像。
结果
使用与供应商无关的软件可以在>92%的儿童中测量短轴径向和圆周应变（ε）和心尖四腔室纵向 ε。整体圆周和纵向 ε 的观察者内和观察者间变异系数范围为 7.1%至 15.3%，径向 ε 的变异系数范围为 23.9%至 30.2%。与使用以 30 帧/秒存储的 GE 图像相比，使用 GE 图像以采集帧速率获得的应变值略高。与特定供应商的软件相比，与供应商无关的软件获得的纵向 ε 和更高的圆周应变值更高。与 EchoPAC 相比，与供应商无关的软件获得的径向应变值较低，与 QLAB 相比，与供应商无关的软件获得的径向应变值较高。
结论
与供应商无关的软件衍生的 ε 是可行的，对于使用来自不同超声系统的图像进行研究和多中心研究测量心肌变形可能具有潜在价值，尤其是对于纵向变形。然而，圆周应变的系统偏差和径向应变测量的高变异性仍然存在问题。
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