Franklin Dermatology Group, TN 37067, USA.
Dermatol Clin. 2011 Jan;29(1):53-62. doi: 10.1016/j.det.2010.08.011.
Chagas disease, or American trypanosomiasis, is a parasitic infection caused by the flagellate protozoan Trypanosoma cruzi, an organism that is endemic to Latin America. While Chagas disease is primarily a vector-borne illness, new cases are emerging in non-endemic areas due to globalization of immigration and non-vectorial transmission routes. This article discusses the mode of transmission, evolving epidemiology, pathogenesis, diagnosis, treatment and prevention and control of the disease.
恰加斯病,也称美洲锥虫病,是一种由鞭毛原生动物克氏锥虫引起的寄生虫感染,该生物体在拉丁美洲流行。虽然恰加斯病主要是一种媒介传播的疾病,但由于移民全球化和非媒介传播途径的出现,非流行地区也出现了新的病例。本文讨论了该病的传播方式、不断变化的流行病学、发病机制、诊断、治疗和预防控制。