Rok 调控枯草芽孢杆菌 168 架构复杂的菌落发育过程中 yuaB 的表达。
Rok regulates yuaB expression during architecturally complex colony development of Bacillus subtilis 168.
机构信息
University of Groningen, Nijenborgh 7, 9747 AG Groningen, Netherlands.
出版信息
J Bacteriol. 2011 Feb;193(4):998-1002. doi: 10.1128/JB.01170-10. Epub 2010 Nov 19.
Abstract
Transcriptome analysis of a Bacillus subtilis rok strain that showed reduced complex colony structure formation revealed significant downregulation of the yuaB gene. Overexpression of yuaB restored structure formation in the rok strain. We show that transcription of yuaB is indirectly regulated by Rok, independently from its previously described AbrB-dependent regulation.
摘要
转录组分析表明，枯草芽孢杆菌 rok 菌株的复杂菌落结构形成减少，yuaB 基因显著下调。yuaB 的过表达恢复了 rok 菌株的结构形成。我们表明，yuaB 的转录受 Rok 的间接调控，与之前描述的 AbrB 依赖性调控无关。
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