枯草芽孢杆菌和嗜热好氧芽胞杆菌 AC6 σ(D)蛋白的 DNA 结合特性。
DNA-binding properties of the Bacillus subtilis and Aeribacillus pallidus AC6 σ(D) proteins.
机构信息
Department of Microbiology, Wing Hall, Cornell University, Ithaca, NY 14853-8101, USA.
出版信息
J Bacteriol. 2011 Jan;193(2):575-9. doi: 10.1128/JB.01193-10. Epub 2010 Nov 19.
Abstract
σ(D) proteins from Aeribacillus pallidus AC6 and Bacillus subtilis bound specifically, albeit weakly, to promoter DNA even in the absence of core RNA polymerase. Binding required a conserved CG motif within the -10 element, and this motif is known to be recognized by σ region 2.4 and critical for promoter activity.
摘要
来自苍白杆菌 AC6 和枯草芽孢杆菌的σ(D)蛋白即使在没有核心 RNA 聚合酶的情况下也能特异性地（尽管较弱地）结合到启动子 DNA 上。结合需要-10 元件内的保守 CG 基序，该基序已知被σ区 2.4 识别，并且对启动子活性至关重要。
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