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酷似腹腔脓肿的基底样(泄殖腔源性)癌:1例报告及文献复习

Basaloid (Cloacogenic) Carcinoma Mimicking Intraabdominal Abscess: Report of a Case and Review of the Literature.

作者信息

Akbulut Sami, Cakabay Bahri, Sezgin Arsenal, Ozmen Cihan Akgul

机构信息

Department of Surgery, Diyarbakır Education and Research Hospital, Diyarbakır, Turkey.

出版信息

Case Rep Gastroenterol. 2009 Aug 28;3(2):248-254. doi: 10.1159/000229755.

Abstract

Cloacogenic carcinoma (CC, basaloid carcinoma) generally occurs around the dentate line, rarely it can arise from the other sides of the colon. There are only 5 cases of CC located outside the anal canal in the literature. The first occurrence of a CC presents as intraabdominal abscess. We describe a 23-year-old male patient who was admitted with fever and severe abdominal pain. Computed tomography imaging showed diffuse wall thickening about 10-11 cm above the rectosigmoid junction, intraabdominal abscess and a soft tissue lession covering the pelvis with a size of 8 × 8.5 cm including cystic necrotic areas. We performed Hartman procedure since the mass was nonresectable. Histopathological examination showed CC. In total, three times radiotherapy and a concurrent three-drug regimen of irinotecan, fluorouracil and folinic acid chemotherapy were administered for 6 weeks. As a result, the patient was lost because of multiple organ dysfunction syndrome that developed 3 months after radio-chemotherapy.

摘要

泄殖腔源性癌(CC,基底样癌)通常发生在齿状线周围,很少能起源于结肠的其他部位。文献中仅有5例CC位于肛管外。首例CC表现为腹腔内脓肿。我们描述了一名23岁男性患者,因发热和严重腹痛入院。计算机断层扫描成像显示,在直肠乙状结肠交界处上方约10 - 11厘米处肠壁弥漫性增厚,腹腔内有脓肿,盆腔有一个大小为8×8.5厘米的软组织病变,包括囊性坏死区域。由于肿块无法切除,我们实施了哈特曼手术。组织病理学检查显示为CC。总共进行了3次放疗,并同时采用伊立替康、氟尿嘧啶和亚叶酸三联化疗方案,持续6周。结果,患者在放化疗后3个月因多器官功能障碍综合征死亡。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af41/2988965/2741f422cbdd/crg0003-0248-f01.jpg

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