Department of Interventional Radiology, Seoul National University Bundang Hospital, Seongnam, Korea.
Gut Liver. 2010 Sep;4 Suppl 1(Suppl 1):S19-24. doi: 10.5009/gnl.2010.4.S1.S19. Epub 2010 Sep 10.
The use of self-expanding metallic stents in the upper gastrointestinal tract, placed under radiologic imaging or endoscopic guidance, is the current treatment of choice for the palliation of malignant gastrointestinal outlet obstructions. Advances in metallic stent design and delivery systems have progressed to the stage where this treatment is now considered a minimally invasive therapy. Metallic stent placement will broaden further into the field of nonsurgical therapy for the gastrointestinal tract. To date, metallic stents placed in the esophagus, gastric outlet, colorectum, and bile ducts are not intended to be curative, but rather to provide a palliative treatment for obstructions. The evolution of metallic stent technology will render such procedures not only palliative but also therapeutic, by enabling local drug delivery, and the use of biodegradable materials will reduce procedure-related complications.
自膨式金属支架在上消化道的应用,在放射影像学或内镜引导下放置,是目前缓解恶性胃肠道出口梗阻的首选治疗方法。金属支架设计和输送系统的进步已经发展到这样一个阶段,即这种治疗现在被认为是一种微创疗法。金属支架的放置将进一步扩展到胃肠道的非手术治疗领域。迄今为止,放置在食管、胃出口、结肠直肠和胆管中的金属支架不是为了治愈,而是为了提供梗阻的姑息性治疗。金属支架技术的发展将使这些手术不仅具有姑息性,而且具有治疗性,通过实现局部药物输送,并使用可生物降解材料减少与手术相关的并发症。