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营养基因组学在皮肤健康中的应用:营养保健品还是药妆品?

Application of nutrigenomics in skin health: nutraceutical or cosmeceutical?

作者信息

Subbiah M T Ravi

机构信息

Department of Internal Medicine, University of Cincinnati Medical Center, Cincinnati, Ohio, USA.

出版信息

J Clin Aesthet Dermatol. 2010 Nov;3(11):44-6.


DOI:
PMID:21103317
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2989812/
Abstract

Nutrigenomics is a growing field related to genetic testing based on the documentation of genetic mutations in an individual, giving us the ability to correct metabolic imbalances (personalized medicine) through specific dietary supplements or nutraceuticals. An off-shoot of nutrigenomics called dermagenetics (testing for selected genetic mutations related to skin health followed by advocating the use of either nutraceuticals or skin creams enriched by cosmeceuticals) is heading toward commercialization at a rapid rate by directly targeting the public. Although this growth represents an opportunity to explore the benefits of genetic advances in skin health, it is essential that the science, product claims, and ethical standards be critically evaluated and clear national guidelines be set in order to protect the consumer.

摘要

营养基因组学是一个不断发展的领域,它与基于个体基因突变记录的基因检测相关,使我们有能力通过特定的膳食补充剂或营养保健品来纠正代谢失衡(个性化医疗)。营养基因组学的一个分支称为皮肤遗传学(检测与皮肤健康相关的特定基因突变,然后提倡使用富含药妆成分的营养保健品或护肤霜),正通过直接面向公众的方式迅速走向商业化。尽管这种增长为探索基因技术在皮肤健康方面的益处提供了机会,但至关重要的是,要对相关科学、产品宣称和道德标准进行严格评估,并制定明确的国家指导方针,以保护消费者。

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本文引用的文献

[1]
An antiinflammatory dietary mix modulates inflammation and oxidative and metabolic stress in overweight men: a nutrigenomics approach.

Am J Clin Nutr. 2010-2-24

[2]
Microemulsions and nanoemulsions: novel vehicles for whitening cosmeceuticals.

J Biomed Nanotechnol. 2009-8

[3]
Cosmeceuticals: undefined, unclassified, and unregulated.

Clin Dermatol. 2009

[4]
Beyond tretinoin: cosmeceuticals for aging skin.

J Drugs Dermatol. 2009-7

[5]
An oral nutraceutical containing antioxidants, minerals and glycosaminoglycans improves skin roughness and fine wrinkles.

Int J Cosmet Sci. 2009-6-30

[6]
Nutrigenomic studies of effects of Chlorella on subjects with high-risk factors for lifestyle-related disease.

J Med Food. 2008-9

[7]
Efficacy and safety of innovative cosmeceuticals.

Clin Dermatol. 2008

[8]
Nanostructured novel carrier for topical application.

Clin Dermatol. 2008

[9]
Understanding the nutrigenomic definitions and concepts at the food-genome junction.

OMICS. 2008-12

[10]
Cosmeceuticals for the attenuation of extrinsic and intrinsic dermal aging.

J Drugs Dermatol. 2008-2

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