Department of Pharmaceutical Technology, Faculty of Pharmaceutical Sciences, Prince of Songkla University, Songkhla 90112, Thailand.
J Biomed Nanotechnol. 2009 Aug;5(4):373-83. doi: 10.1166/jbn.2009.1046.
For Asian women, white skin is preferable. During the last decade, skin whitening products appear to be the largest and continually growing segment in skin-care market in Asia and have an impaction of economic worth. Skin whitening or lightening agents are as cosmetics which act as a drug-like benefit since melanin producing process of the skin is disturbed and can be classified as cosmeceuticals. To increase efficiency, novel vehicles are necessary for skin penetration enhancement of these agents. Microemulsions and nanoemulsions are one of useful nanocarriers for skin application in view of achieving efficiency of the active substances. Moreover, they can be formulated with ease for active ingredient incorporation, high stability and good appearance. In this review article, applications of well-known whitening or lightening agents were summarized. In addition, the use of microemulsions and nanoemulsions as novel vehicles for whitening products were discussed.
对于亚洲女性来说，白皙的皮肤更受欢迎。在过去十年中，美白产品似乎是亚洲护肤品市场中规模最大且持续增长的部分，具有巨大的经济价值。美白或淡斑产品作为化妆品，其功效类似于药物，因为它们扰乱了皮肤中黑色素的产生过程，因此可以被归类为药妆品。为了提高功效，需要新型载体来增强这些物质的皮肤穿透性。鉴于可以提高活性物质的效率，微乳液和纳米乳液是用于皮肤应用的有用纳米载体之一。此外，它们可以轻松配制以包含活性成分、具有高稳定性和良好的外观。在这篇综述文章中，总结了一些知名的美白或淡斑成分的应用。此外，还讨论了将微乳液和纳米乳液用作新型美白产品载体的应用。
