干扰素处理的牛气管器官培养物中的抗病毒活性。
Antiviral activity in interferon-treated bovine tracheal organ cultures.
作者信息
Fulton R W, Root S K
出版信息
Infect Immun. 1978 Aug;21(2):672-3. doi: 10.1128/iai.21.2.672-673.1978.
Abstract
The effect of bovine interferon on the replication of infectious bovine rhinotracheitis virus and vesicular stomatitis virus in bovine tracheal organ cultures was studied. After treatment of tracheal organ cultures with interferon, inhibition of infectious bovine rhinotracheitis virus and vesicular stomatitis virus replication was observed. This tracheal organ system may be useful in determining the in vivo response to interferon for viral infections of the bovine respiratory tract.
摘要
研究了牛干扰素对牛传染性鼻气管炎病毒和水疱性口炎病毒在牛气管器官培养物中复制的影响。在用干扰素处理气管器官培养物后，观察到牛传染性鼻气管炎病毒和水疱性口炎病毒复制受到抑制。这种气管器官系统可能有助于确定牛呼吸道病毒感染时体内对干扰素的反应。
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本文引用的文献
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Am J Vet Res. 1968 Jul;29(7):1355-62.
2
Interferon in nasal secretions and sera of calves after intranasal administration of avirulent infectious bovine rhinotracheitis virus: association of interferon in nasal secretions with early resistance to challenge with virulent virus.鼻内接种无毒力传染性牛鼻气管炎病毒后犊牛鼻分泌物和血清中的干扰素：鼻分泌物中干扰素与对强毒病毒攻击的早期抵抗力的关联
Infect Immun. 1972 May;5(5):699-706. doi: 10.1128/iai.5.5.699-706.1972.
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