从兽疫链球菌 MTCC 3523 生产透明质酸及其伤口愈合活性。
Production of hyaluronic acid from Streptococcus zooepidemicus MTCC 3523 and its wound healing activity.
机构信息
School of Life Sciences, North Maharashtra University, PO Box: 80, Jalgaon 425001, India.
出版信息
J Biosci Bioeng. 2011 Mar;111(3):286-8. doi: 10.1016/j.jbiosc.2010.10.012. Epub 2010 Nov 24.
PMID:21109488
Abstract
Exopolysaccharide produced and purified from Streptococcus zooepidemicus MTCC 3523 was identified as hyaluronic acid (HA) based on IR and NMR spectroscopy while its Mw was found to be 5.38 × 10(5)Da. HA produced passed bacterial endotoxin test and showed significant wound healing activity in Wistar rats on 12th and 16th day.
摘要
从兽疫链球菌 MTCC 3523 中提取和纯化的胞外多糖被鉴定为透明质酸（HA），这是基于红外和核磁共振波谱得出的结论，同时其分子量被发现为 5.38×10(5)Da。所产生的 HA 通过了细菌内毒素测试，并在第 12 天和第 16 天的 Wistar 大鼠中显示出显著的伤口愈合活性。
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