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金刚石纳米颗粒暴露对大型溞内部结构和繁殖的影响。

Effects of diamond nanoparticle exposure on the internal structure and reproduction of Daphnia magna.

机构信息

LNEG-Laboratório Nacional de Energia e Geologia, Lisboa, Portugal.

出版信息

J Hazard Mater. 2011 Feb 15;186(1):265-71. doi: 10.1016/j.jhazmat.2010.10.115. Epub 2010 Nov 9.

DOI:10.1016/j.jhazmat.2010.10.115
PMID:21111531
Abstract

Nanomaterials have significant technological advantages but their release into the environment also carry potential ecotoxicological risks. Carbon-based nanoparticles and particularly diamond nanoparticles have numerous industrial and medical applications. The aim of the present study was to evaluate the toxic effects of diamond nanoparticles with an average particle size of 20 nm on the survival, reproduction and tissue structure of the freshwater crustacean Daphnia magna. The chronic toxicity test results showed 100% mortality at concentrations higher than 12.5 mg l(-1) and that reproduction inhibition occurred in concentrations higher than 1.3 mg l(-1). Light microscopy showed that diamond nanoparticles adhere to the exoskeleton surface and accumulate within the gastrointestinal tract, suggesting that food absorption by the gut cells may be blocked. The results support the use of chronic approaches in environmental protection as part of an integrated environmental monitoring and assessment strategy.

摘要

纳米材料具有显著的技术优势,但它们释放到环境中也可能带来潜在的生态毒理学风险。碳基纳米粒子,尤其是金刚石纳米粒子,具有许多工业和医疗应用。本研究旨在评估平均粒径为 20nm 的金刚石纳米粒子对淡水甲壳类动物大型溞(Daphnia magna)存活、繁殖和组织结构的毒性影响。慢性毒性试验结果表明,浓度高于 12.5mg/L 时,死亡率达到 100%,浓度高于 1.3mg/L 时,繁殖受到抑制。光学显微镜观察显示,金刚石纳米粒子附着在外壳表面并在胃肠道内积累,表明肠道细胞的食物吸收可能被阻断。研究结果支持在环境保护中采用慢性方法,作为综合环境监测和评估策略的一部分。

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