Padmavathi O, Reddy G P, Reddy G R, Reddanna P
Department of Zoology, Sri Venkateswara University, Tirupati, India.
Biochem Int. 1990;20(3):455-61.
The biosynthetic potential of prostaglandins (PGs) was measured in ovarian follicles and corpus luteum of sheep ovary. The total prostaglandins formed under non-enzymatic conditions were much lower in comparison to that formed using native GSTs. When the GSTs of ovarian follicles were employed, the major prostaglandin formed was PGE2 (81.22%) followed by PGD2 (16.9%) and PGF2 alpha (1.87%). In case of corpus luteum, prostaglandin formed was PGF2 alpha (59.01%). Since PGF2 alpha was demonstrated to be the luteolytic factor, the present study indicates the formation of luteolytic factor in the ovarian tissue itself.
在绵羊卵巢的卵泡和黄体中测定了前列腺素（PGs）的生物合成潜力。与使用天然谷胱甘肽S-转移酶（GSTs）形成的前列腺素相比，在非酶促条件下形成的总前列腺素要低得多。当使用卵巢卵泡的GSTs时，形成的主要前列腺素是PGE2（81.22%），其次是PGD2（16.9%）和PGF2α（1.87%）。在黄体的情况下，形成的前列腺素是PGF2α（59.01%）。由于PGF2α被证明是黄体溶解因子，本研究表明在卵巢组织自身中形成了黄体溶解因子。
