比较两种商业分子检测方法与实验室开发的分子检测方法在诊断艰难梭菌感染中的应用。
Comparison of two commercial molecular assays to a laboratory-developed molecular assay for diagnosis of Clostridium difficile infection.
机构信息
Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.
出版信息
J Clin Microbiol. 2011 Feb;49(2):725-7. doi: 10.1128/JCM.01028-10. Epub 2010 Dec 1.
Abstract
We compared two commercial PCR assays, the Prodesse ProGastro CD assay and the BD GeneOhm Cdiff assay, with a laboratory-developed Clostridium difficile toxin PCR assay with previously established performance characteristics. Results of all methods were in agreement for 333 (96%) of 346 stool specimens. No significant difference in performance among the assays was found (P values, >0.05).
摘要
我们将两种商业 PCR 检测方法，Prodesse ProGastro CD 检测法和 BD GeneOhm Cdiff 检测法，与实验室开发的具有先前建立的性能特征的艰难梭菌毒素 PCR 检测法进行了比较。所有方法的结果在 346 份粪便标本中的 333 份（96%）中是一致的。在检测方法之间没有发现性能的显著差异（P 值均＞0.05）。
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