Palombo D, Lucertini G, Pane B, Mazzei R, Spinella G, Brasesco P C
Vascular and Endovascular Surgery Unit, San Martino University Hospital, Genoa, Italy.
J Cardiovasc Surg (Torino). 2010 Dec;51(6):777-82.
Screening for abdominal aortic aneurysms (AAAs) has been carried out in an area of Genoa (Italy) for subjects aged 65 years or more to evaluate prevalence of this disease.
Between March 2007 and September 2009 8234 subjects were screened. Ultrasound examination of the abdominal aorta and the iliac arterial segments was carried out on each subject and all data related to risk factors were collected.
Five hundreds-twelve (6.2%) subjects were found to have an AAA: 469 (10.8%) males and 43 (1.1%) females (significant difference, P < 0.01). Based on the aortic diameter, 403 (4.9%), 80 (1.0%) and 29 (0.3%) had an AAA of 3.0-3.9 cm, 4.0-4.9 cm and ≥ 5.0 cm diameter, respectively. With regards to risk factors, family history of cardiovascular disease only resulted more frequent in subjects with AAA than in those without AAA.
The prevalence of patients with AAA (6.2%) was similar to previously published estimates. Nevertheless, AAA resulted very high in males. This observation is likely due to screening in a city with a very high percentage of elderly subjects. Family predisposition to cardiovascular disease resulted significant risk factor for AAA. Results of our epidemiological study provide evidence of the usefulness of AAA screening thanks to early diagnosis and appropriate treatment of AAA.
在意大利热那亚的一个地区,对65岁及以上的人群进行腹主动脉瘤(AAA)筛查,以评估该疾病的患病率。
2007年3月至2009年9月期间,对8234名受试者进行了筛查。对每位受试者进行腹主动脉和髂动脉段的超声检查,并收集所有与危险因素相关的数据。
发现512名(6.2%)受试者患有腹主动脉瘤:男性469名(10.8%),女性43名(1.1%)(差异有统计学意义,P<0.01)。根据主动脉直径,分别有403名(4.9%)、80名(1.0%)和29名(0.3%)的腹主动脉瘤直径为3.0 - 3.9厘米、4.0 - 4.9厘米和≥5.0厘米。关于危险因素,有腹主动脉瘤的受试者中,仅心血管疾病家族史比无腹主动脉瘤的受试者更常见。
腹主动脉瘤患者的患病率(6.2%)与先前发表的估计值相似。然而,腹主动脉瘤在男性中的患病率非常高。这一观察结果可能归因于在一个老年受试者比例非常高的城市进行筛查。心血管疾病的家族易感性是腹主动脉瘤的一个重要危险因素。我们的流行病学研究结果证明了腹主动脉瘤筛查的有用性,这得益于腹主动脉瘤的早期诊断和适当治疗。