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联合生理参数在急性内科患者病情恶化早期识别中的应用

The use of combined physiological parameters in the early recognition of the deteriorating acute medical patient.

作者信息

Cuthbertson B H, Boroujerdi M, Prescott G

机构信息

Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, Ontario, Canada.

出版信息

J R Coll Physicians Edinb. 2010 Mar;40(1):19-25. doi: 10.4997/JRCPE.2010.105.

Abstract

BACKGROUND

Early warning scores (EWS) are widely used to allow early recognition of the deteriorating patient. We aimed to test their ability to predict major deterioration in medical patients.

METHODS

Two cohorts were prospectively identified who were admitted to an acute medical admissions unit and to the respiratory unit but not admitted to the intensive care unit (ICU): medical-non ICU and respiratory-non ICU groups. Two further cohorts were retrospectively identified that required ICU admission from these units (medical-ICU and respiratory-ICU groups). Discriminant analysis and receiver operating characteristic curves were used to discriminate between groups, and time relationships were analysed.

RESULTS

Heart rate (HR) and respiratory rate (RR) were significantly higher--and oxygen saturation (SaO₂) significantly lower--in the medical-ICU group as compared with the medical non-ICU group, and in the respiratory-ICU group as compared with [corrected] the respiratory-non ICU group. Discriminant functions incorporating HR, RR and SaO₂ performed at least as well as existing EWS systems in predicting ICU admission.

CONCLUSIONS

Commonly used physiological parameters and existing EWS systems are useful at identifying sick patients. The discriminant functions described here appear to have a role in this setting but require validation in future studies.

摘要

背景

早期预警评分(EWS)被广泛用于早期识别病情恶化的患者。我们旨在测试其预测内科患者严重病情恶化的能力。

方法

前瞻性确定了两组患者,他们被收治于急性内科收治单元和呼吸科,但未收入重症监护病房(ICU):内科非ICU组和呼吸科非ICU组。另外通过回顾性研究确定了两组需要从这些单元转入ICU的患者(内科ICU组和呼吸科ICU组)。采用判别分析和受试者工作特征曲线对组间进行区分,并分析时间关系。

结果

与内科非ICU组相比,内科ICU组的心率(HR)和呼吸频率(RR)显著更高,氧饱和度(SaO₂)显著更低;与呼吸科非ICU组相比,呼吸科ICU组的情况相同。包含HR、RR和SaO₂的判别函数在预测ICU入住方面至少与现有的EWS系统表现相当。

结论

常用的生理参数和现有的EWS系统有助于识别病情严重的患者。本文所述的判别函数在此情况下似乎有一定作用,但需要在未来研究中进行验证。

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