Queen Elizabeth National Spinal Injuries Unit, Southern General Hospital, 1345 Govan Road, Glasgow G51 4TF, UK.
Eur Spine J. 2011 Mar;20(3):403-7. doi: 10.1007/s00586-010-1628-y. Epub 2010 Dec 3.
Patients with ankylosing spondylitis (AS) are vulnerable to cervical spine fractures. Long-standing pain may mask the symptoms of the fracture. Radiological imaging of the cervical spine may fail to identify the fracture due to the distorted anatomy, ossified ligaments and artefacts leading to delay in diagnosis and increased risk of neurological complications. The objectives are to identify the incidence and risk factors for delay in presentation of cervical spine fractures in patients with AS. Retrospective case series study of all patients with AS and cervical spine fracture admitted over a 12-year period at Queen Elizabeth National Spinal Injuries Unit, Scotland. Results show that total of 32 patients reviewed with AS and cervical spine fractures. In 19 patients (59.4%), a fracture was not identified on plain radiographs. Only five patients (15.6%) presented immediately after the injury. Of the 15 patients (46.9%) who were initially neurologically intact, three patients had neurological deterioration before admission. Cervical spine fractures in patients with long-standing AS are common and usually under evaluated. Early diagnosis with appropriate radiological investigations may prevent the possible long-term neurological cord damage.
强直性脊柱炎(AS)患者易发生颈椎骨折。长期的疼痛可能掩盖骨折的症状。由于解剖结构变形、韧带骨化和伪影,颈椎的放射影像学检查可能无法识别骨折,导致诊断延迟和增加神经并发症的风险。目的是确定 AS 患者颈椎骨折就诊延迟的发生率和危险因素。对苏格兰伊丽莎白女王国家脊柱损伤中心 12 年间收治的所有 AS 合并颈椎骨折患者进行回顾性病例系列研究。结果共回顾了 32 例 AS 合并颈椎骨折患者。在 19 例患者(59.4%)中,平片未发现骨折。仅有 5 例患者(15.6%)在受伤后立即就诊。在最初神经功能完整的 15 例患者(46.9%)中,有 3 例在入院前出现神经功能恶化。长期 AS 患者的颈椎骨折很常见,但通常评估不足。早期诊断并进行适当的影像学检查可能预防潜在的长期脊髓神经损伤。