Department of Microbiology, Medical School, University of Thessaly, Larissa, Greece.
Int J Antimicrob Agents. 2011 Feb;37(2):102-9. doi: 10.1016/j.ijantimicag.2010.10.014. Epub 2010 Dec 4.
Multidrug-resistant Acinetobacter baumannii (MDR-AB) infections are difficult to treat owing to the extremely limited armamentarium. The present review reports all available treatment options against MDR-AB, including single molecules, combination schemes, and alternative modes of antimicrobial administration. Additionally, a group of recently reported peptides with anti-MDR-AB activity is described.
多重耐药鲍曼不动杆菌(MDR-AB)感染由于治疗手段极其有限而难以治疗。本综述报告了所有针对 MDR-AB 的可用治疗选择,包括单分子、联合方案和抗菌药物的替代给药方式。此外,还描述了一组最近报道的具有抗 MDR-AB 活性的肽。