癫痫：抗癫痫药物与自杀行为风险。

Epilepsy: Risk of suicidal behavior with antiepileptic drugs.

机构信息

Department of Neuroscience, Mental Health and Sensory Functions, Suicide Prevention Center, Sant'Andrea Hospital, Sapienza University of Rome, Via di Grottarossa 1035, Rome, Italy.

出版信息

Nat Rev Neurol. 2010 Dec;6(12):651-3. doi: 10.1038/nrneurol.2010.165.

DOI:10.1038/nrneurol.2010.165

PMID:21131913

Abstract

Antiepileptic drugs (AeDs) are receiving increasing attention for a possible association with suicidal thoughts and behaviors. Several recent studies examining this association, however, have yielded inconsistent findings, particularly in terms of the risk of suicidal behavior conferred by specific AeDs. In patients with epilepsy, heightened suicide risk is also attributable to comorbid psychiatric conditions.

摘要

抗癫痫药物（AeDs）因其可能与自杀意念和行为有关而受到越来越多的关注。然而，最近几项研究检查了这种关联，结果发现并不一致，特别是特定 AeDs 导致自杀行为的风险。在癫痫患者中，自杀风险增加也归因于合并的精神疾病。