Sousa Leandro, Gonorazky Sergio
Hospital Privado de Comunidad de Mar del Plata, Argentina.
Arch Argent Pediatr. 2010 Oct;108(5):e108-10. doi: 10.1590/S0325-00752010000500012.
In 1988, Ouvrier and Billson described four children with a condition they termed "benign paroxysmal tonic upgaze syndrome". The clinical picture is characterized by the appearance, in the first months of life, of episodes of paroxysmal upgaze deviation of varying duration, and without alteration of consciousness. Fixation nystagmus is observed when trying to look down. Episodes disappear during sleep. The neurological examination is usually normal, except for mild ataxia. In its idiopatic way, the syndrome tends to spontaneous recovery, but secondary types with different evolution should be rule out. We report two patients, one with Down Syndrome, and we analyze clinical aspects, evolution and differential diagnosis.
1988年，奥弗里尔和比尔森描述了4名患有他们称为“良性阵发性强直性上视综合征”的儿童。临床表现为在出生后的头几个月出现不同持续时间的阵发性上视偏斜发作，且意识无改变。试图向下看时可观察到注视性眼球震颤。发作在睡眠期间消失。除轻度共济失调外，神经系统检查通常正常。该综合征以特发性方式发病，倾向于自发恢复，但应排除具有不同病程的继发性类型。我们报告了两名患者，其中一名患有唐氏综合征，并分析了临床特征、病程及鉴别诊断。
