ASL BAT, Andria, Bari, Italy.
Aliment Pharmacol Ther. 2011 Feb;33(3):358-65. doi: 10.1111/j.1365-2036.2010.04530.x. Epub 2010 Dec 7.
Ulcerative colitis with diverticulosis (UCD), segmental colitis associated with diverticulosis (SCAD) and acute uncomplicated diverticulitis (AUD) may affect the same colonic regions, but the real incidence of these entities in clinical practice is unknown.
To assess the incidence and the endoscopic findings of UCD, SCAD and AUD.
From January 2004 to June 2009, 8525 consecutive colonoscopies were performed. Diagnosis of the diseases was based on specific endoscopic and histological (UCD and SCAD), and on endoscopic and radiological (AUD) patterns.
Ulcerative colitis with diverticulosis was diagnosed in 25 patients (0.3%), SCAD was diagnosed in 129 patients (2%) and AUD was diagnosed in 130 patients (2%). In UCD, the inflammation in colonic area harbouring diverticula always affects the overall colonic mucosa in all cases, involving also diverticular orifices. The endoscopic characteristic of SCAD is that inflammation is mainly detected within the inter-diverticular mucosa without involvement of the diverticular orifices. In AUD, the inflammation affects primarily diverticular orifice and peri-diverticular mucosa.
In clinical practice, the incidence of mucosal inflammation in the presence of colonic diverticular disease is low and endoscopy is the mainstay of differential diagnosis.
溃疡性结肠炎合并憩室炎（UCD）、节段性结肠炎合并憩室炎（SCAD）和急性单纯性憩室炎（AUD）可能累及相同的结肠区域，但这些疾病在临床实践中的实际发生率尚不清楚。
评估 UCD、SCAD 和 AUD 的发病率和内镜表现。
2004 年 1 月至 2009 年 6 月，对 8525 例连续结肠镜检查进行了评估。疾病的诊断基于特定的内镜和组织学（UCD 和 SCAD）以及内镜和放射学（AUD）表现。
25 例（0.3%）患者被诊断为溃疡性结肠炎合并憩室炎，129 例（2%）患者被诊断为节段性结肠炎合并憩室炎，130 例（2%）患者被诊断为急性单纯性憩室炎。在 UCD 中，累及憩室的结肠区域炎症始终累及所有病例的整个结肠黏膜，也累及憩室开口。SCAD 的内镜特征是炎症主要发生在憩室间黏膜内，而不累及憩室开口。在 AUD 中，炎症主要影响憩室开口和憩室周围黏膜。
在临床实践中，结肠憩室病伴黏膜炎症的发生率较低，内镜检查是鉴别诊断的主要手段。
