Department of Oral Medicine, Yonsei University, Seoul, Korea.
Dermatol Surg. 2010 Dec;36 Suppl 4:2161-6. doi: 10.1111/j.1524-4725.2010.01704.x.
To use three-dimensional (3D) laser scanning to elucidate changes in the external facial contour before and after botulinum toxin type A (BoNT-A) injections.
METHODS & MATERIALS: BoNT-A was injected into 15 volunteers as a treatment for lower facial contouring. A total of 25 U of BoNT-A was injected into each side of the masseter muscle bilaterally. On each side, it was injected into two points at the center of the lower third of the masseter muscle separated by 1 cm. The clinical effects of BoNT-A were evaluated by performing 3D laser scans before and 4, 8, 12, and 24 weeks after the injection.
The mean values of the volume and widths of the most prominent area at each time point differed significantly before and 4, 8, 12, and 24 weeks after the injection.
The volumes and widths of the most prominent areas of the lower face (masseter muscle) were significantly lower 4, 8, 12, and 24 weeks after injecting BoNT-A than before the injection. The mean values of the volume and widths of the most prominent area were 2,176.93 mm(3) and 2.39 mm less, respectively, 24 weeks after the injection than before.
使用三维（3D）激光扫描来阐明肉毒毒素 A（BoNT-A）注射前后的外部面部轮廓变化。
BoNT-A 被注射到 15 名志愿者中，作为治疗下脸部轮廓的方法。总共有 25U 的 BoNT-A 被双侧注射到咬肌的每侧的两个点。在每一侧，它被注射到咬肌下三分之一的中心的两个点，两点之间相隔 1 厘米。在注射前和注射后 4、8、12 和 24 周进行 3D 激光扫描，评估 BoNT-A 的临床效果。
在注射前和注射后 4、8、12 和 24 周，每个时间点的最大突出区域的体积和宽度的平均值差异有统计学意义。
在注射 BoNT-A 后 4、8、12 和 24 周，下脸（咬肌）的最大突出区域的体积和宽度明显低于注射前。与注射前相比，注射后 24 周时最大突出区域的体积和宽度的平均值分别减少了 2176.93mm(3)和 2.39mm。
