Ferri G L, Sabani A, Abelli L, Polak J M, Dahl D, Portier M M
Department of Anatomy, Tor Vergata University, Rome, Italy.
Brain Res. 1990 May 7;515(1-2):331-5. doi: 10.1016/0006-8993(90)90618-l.
Two major neuronal populations were revealed in rat dorsal root ganglia, immunoreactive for either peripherin, or neurofilament triplet proteins (adult L2 ganglia: 66.2% and 25.6%, mainly small and large diameter cells, respectively), together with a minor, double-immunostained population (L2: 8.1%, mainly intermediate-size neurons). After capsaicin treatment, a striking expansion in the latter population was seen (L2: 22.0%) together with a significant increase in size, restricted to the same population and the (remaining) peripherin-only immunoreactive neurons. Calcitonin gene-related peptide (CGRP) immunoreactivity was revealed in neurons of all 3 groups, in both normal and capsaicin-treated rats.
在大鼠背根神经节中发现了两种主要的神经元群体，分别对外周蛋白或神经丝三联体蛋白呈免疫反应（成年L2神经节：分别为66.2%和25.6%，主要是小直径和大直径细胞），还有一小部分双免疫染色群体（L2：8.1%，主要是中等大小的神经元）。辣椒素处理后，后一群体显著扩大（L2：22.0%），并且大小显著增加，仅限于同一群体以及（剩余的）仅对外周蛋白呈免疫反应的神经元。在正常和辣椒素处理的大鼠中，三组神经元均显示降钙素基因相关肽（CGRP）免疫反应性。
