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阿根廷布宜诺斯艾利斯地区银屑病关节炎的发病和流行情况:一项基于 6 年健康管理组织的研究。

Incidence and prevalence of psoriatic arthritis in Buenos Aires, Argentina: a 6-year health management organization-based study.

机构信息

Servicio de Clinica Meédica, Hospital Italiano de Buenos Aires, Ciudad Autónoma de Buenos Aires 1181, Argentina.

出版信息

Rheumatology (Oxford). 2011 Apr;50(4):729-34. doi: 10.1093/rheumatology/keq369. Epub 2010 Dec 6.

Abstract

OBJECTIVES

Studies regarding epidemiology of PsA are lacking in Latin America. We estimated the incidence and prevalence of PsA in a University Hospital-based Health Management Organization in Buenos Aires [Hospital Italiano Medical Care Program (HIMCP)].

POPULATION

for incidence calculation, the population at risk was all adult members of the HIMCP, with continuous affiliation for at least 1 year from January 2000 to January 2006. Each person was followed until he/she voluntarily left the HIMCP, death or finalization of the study (final dates) contributing time at risk since January 2000 or enrolment date (whichever occurred later) to that final date. Case ascertainment: medical records of all patients with the problem psoriasis and/or PsA in the HIMCP problem-oriented computer-based patient record system, or registered in rheumatologists and/or dermatologists databases, were revised. Patients fulfilling CASPAR criteria were included.

STATISTICAL ANALYSIS

incidence rate (IR) was calculated with 95% CIs. Cumulative prevalence was estimated on 1 January 2006 (denominator population ==88,112).

RESULTS

In the study period, 138,288 persons contributed a total of 558,878 person-years, of whom 35 developed PsA (IR 6.26; 95% CI 4.2, 8.3 cases per 100,000 person-years). There were 12 females: IR 3.64 (95% CI 1.6, 5.7) cases per 100,000 person-years; and 23 males: IR 10.02 (95% CI 5.9, 14.1) cases per 100,000 person-years. On 1 January 2006, 65 prevalent cases were identified: prevalence 74 (95% CI 57, 94) cases per 100,000 members.

CONCLUSIONS

The incidence and prevalence of PsA in this Latin American country was similar to that reported in other studies from Europe and the USA.

摘要

目的

关于银屑病关节炎(PsA)的流行病学研究在拉丁美洲较为匮乏。我们评估了布宜诺斯艾利斯一家大学医院医疗保健组织(HIMCP)中 PsA 的发病率和患病率。

人群

为了计算发病率,风险人群为 HIMCP 的所有成年成员,他们在 2000 年 1 月至 2006 年 1 月期间至少连续参保 1 年。每个人都在 HIMCP 中自愿离开、死亡或研究结束(最终日期)之前被随访,自 2000 年 1 月起或参保日期(以较晚者为准)起计入风险时间。病例确定:对 HIMCP 基于问题的计算机患者记录系统中所有患有银屑病和/或 PsA 问题的患者的病历,或登记在风湿病学家和/或皮肤科医生数据库中的患者病历进行了复查。符合 CASPAR 标准的患者被纳入研究。

统计学分析

发病率(IR)用 95%置信区间(CI)计算。2006 年 1 月 1 日的累积患病率(分母人口数=88112)。

结果

在研究期间,138288 人共提供了 558878 人年的随访,其中 35 人发生了 PsA(IR 6.26;95%CI 4.2,8.3 例/10 万患者年)。其中有 12 名女性:IR 3.64(95%CI 1.6,5.7)例/10 万患者年;23 名男性:IR 10.02(95%CI 5.9,14.1)例/10 万患者年。2006 年 1 月 1 日,共发现 65 例现患病例:患病率为 74(95%CI 57,94)例/10 万成员。

结论

在这个拉丁美洲国家,PsA 的发病率和患病率与欧洲和美国的其他研究报道相似。

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