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解释冠心病中的性别差异：是否是时候将关注点从雌激素假说转移到铁假说？

Explaining sex difference in coronary heart disease: is it time to shift from the oestrogen hypothesis to the iron hypothesis?

机构信息

Comando Brigata Alpina Julia, Medical Service, Udine, Italy.

出版信息

J Cardiovasc Med (Hagerstown). 2011 Jan;12(1):64-5. doi: 10.2459/JCM.0b013e3283403942.

DOI:10.2459/JCM.0b013e3283403942
PMID:21135587
Abstract

We suggest that lower body iron stores, and not the loss of ovarian function, explain the differences between men and women, and between fertile and menopausal women in the development of coronary heart disease.

摘要

我们认为，是体内铁储存量较低，而不是卵巢功能丧失，导致了冠心病在男性、女性、绝经前女性和绝经后女性之间的发展差异。

相似文献

1
Explaining sex difference in coronary heart disease: is it time to shift from the oestrogen hypothesis to the iron hypothesis?解释冠心病中的性别差异：是否是时候将关注点从雌激素假说转移到铁假说？
J Cardiovasc Med (Hagerstown). 2011 Jan;12(1):64-5. doi: 10.2459/JCM.0b013e3283403942.
2
[An alternative hypothesis explaining the gender differences in risk of coronary heart disease].
Tidsskr Nor Laegeforen. 2002 Aug 10;122(18):1783-7.
3
The iron-heart disease connection: is it dead or just hiding?铁与心脏病的关联：它已不存在还是只是隐藏起来了？
Ageing Res Rev. 2004 Jul;3(3):355-67. doi: 10.1016/j.arr.2004.04.002.
4
Risk of coronary heart disease in women after menopause.绝经后女性患冠心病的风险。
J Indian Med Assoc. 2001 Sep;99(9):478-80, 482.
5
Bone mineral density in premenopausal women with oestrogen deficiency and symptomatic coronary heart disease.
Br J Clin Pract. 1996 Dec;50(8):450-3.
6
Body iron stores and the risk of coronary heart disease.体内铁储备与冠心病风险
N Engl J Med. 1994 Apr 21;330(16):1119-24. doi: 10.1056/NEJM199404213301604.
7
Body iron stores and gender differences in risk factors for coronary heart disease.
Maturitas. 2010 May;66(1):107. doi: 10.1016/j.maturitas.2010.02.001. Epub 2010 Feb 24.
8
[Ischemic cardiopathy in women].
Rev Esp Cardiol. 1991 Oct;44(8):500-10.
9
Coronary heart disease in postmenopausal women; the role of endogenous estrogens and their receptors.绝经后女性的冠心病；内源性雌激素及其受体的作用。
Hormones (Athens). 2007 Jan-Mar;6(1):9-24.
10
[Differences and similarities in ischemic heart disease in men and women].[男性和女性缺血性心脏病的异同]
Folia Med Cracov. 1991;32(1-2):43-56.

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