Grabenstein J D, Smith L J, Watson R R, Summers R J
School of Pharmacy, University of North Carolina, Chapel Hill 27599-7360.
Public Health Rep. 1990 May-Jun;105(3):311-6.
A comprehensive assessment of the immunization status of 2,451 adults was carried out at Walter Reed Army Medical Center's Allergy-Clinical Immunology Service, Washington, DC, during an influenza immunization program from October 1985 through February 1986. More than 66 percent of those screened needed either immunization other than for influenza, or an immunologic test, a decline from 72 percent noted during a 1984-85 influenza immunization program. The mean number of interventions was 2.00 per patient in the 1985-86 program and 2.26 during the previous program. Of patients screened in the period 1985-86, 20.5 percent received diphtheria-tetanus toxoids, 15.7 percent received pneumococcal vaccine, and 23.1 percent received a tuberculin skin test. Vaccination or titers for measles were ordered for 10.4 percent, for rubella for 10.9 percent, and for hepatitis B for 20.3 percent. Assessment of those who came to the clinic for influenza vaccination in the second program demonstrated that the needs of some patients had been met in the first program. However, a general lack of immune protection existed in the majority of patients screened in the second program. In both programs, those older than 59 years needed pneumococcal vaccine and diphtheria-tetanus toxoids more frequently than the general population. The means of the numbers of interventions and the percentages of patients needing intervention other than influenza vaccine declined from the first program to the second, suggesting progress in meeting some individual immunization needs in a large and changing ambulatory population.
1985年10月至1986年2月流感免疫计划期间,华盛顿特区沃尔特·里德陆军医疗中心过敏与临床免疫学服务部对2451名成年人的免疫状况进行了全面评估。接受筛查的人群中,超过66%的人需要进行除流感疫苗之外的其他免疫接种或免疫检测,这一比例低于1984 - 1985年流感免疫计划期间记录的72%。1985 - 1986年计划中每位患者的平均干预次数为2.00次,前一个计划期间为2.26次。在1985 - 1986年期间接受筛查的患者中,20.5%接种了白喉 - 破伤风类毒素,15.7%接种了肺炎球菌疫苗,23.1%接受了结核菌素皮肤试验。10.4%的患者被安排进行麻疹疫苗接种或检测,10.9%的患者被安排进行风疹疫苗接种或检测,20.3%的患者被安排进行乙肝疫苗接种或检测。对参加第二个计划中流感疫苗接种门诊的患者评估显示,一些患者在第一个计划中已满足了需求。然而,在第二个计划中接受筛查的大多数患者普遍缺乏免疫保护。在两个计划中,59岁以上的人群比普通人群更频繁地需要肺炎球菌疫苗和白喉 - 破伤风类毒素。从第一个计划到第二个计划,干预次数的均值以及需要除流感疫苗之外干预措施的患者百分比均有所下降,这表明在满足一个庞大且不断变化的门诊人群的部分个体免疫需求方面取得了进展。