Jephcott E H, Lynn R D, Thorburn G D, McMillen I C
Department of Physiology, Monash University, Clayton, Victoria, Australia.
Res Vet Sci. 1990 May;48(3):314-20.
Arterial blood gases, pH and haemoglobin concentrations were monitored for 20 minutes before, during and for 120 minutes after 60 seconds of electroimmobilisation (E-IM) at current strengths of 0 mA (control), 40 mA and 60 mA in 17 Merino ewes (36.3 +/- 1.0 kg) previously prepared with unilateral carotid artery loops. E-IM elicited whole body rigidity. During E-IM, breathing was stopped for 50 +/- 3 seconds (40 mA) and 56 +/- 2 seconds (60 mA). Arterial PO2 decreased to 43.2 +/- 2.4 mmHg (5.68 +/- 0.32 kPa) (40 mA) and 36.4 +/- 1.8 mmHg (60 mA) while arterial PCO2 rose to 59.7 +/- 1.9 mmHg (40 mA) and 69.8 +/- 2.0 mmHg (60 mA). There was a significant fall in arterial pH to 7.272 +/- 0.014 (40 mA) and 7.233 +/- 0.011 (60 mA) during E-IM and arterial haemoglobin increased by 34 +/- 3 per cent and 35 +/- 3 per cent at 40 mA and 60 mA, respectively. All the arterial blood gas and pH changes were significantly greater (P less than 0.05) during E-IM at 60 mA than at 40 mA. Multiple regression analysis indicated that the decrease in arterial PO2 during E-IM was directly related to the latency to breathe while the changes in arterial PCO2 and pH during E-IM were not.2+off
对17只美利奴母羊（体重36.3±1.0千克）进行实验，这些羊之前已制备好单侧颈动脉袢。在电流强度分别为0毫安（对照组）、40毫安和60毫安的情况下，对其进行60秒的电固定（E-IM），在电固定前、期间以及之后120分钟监测动脉血气、pH值和血红蛋白浓度。E-IM引发全身强直。在E-IM期间，呼吸停止50±3秒（40毫安）和56±2秒（60毫安）。动脉血氧分压降至43.2±2.4毫米汞柱（5.68±0.32千帕）（40毫安）和36.4±1.8毫米汞柱（60毫安），而动脉血二氧化碳分压升至59.7±1.9毫米汞柱（40毫安）和69.8±2.0毫米汞柱（60毫安）。在E-IM期间，动脉pH值显著降至7.272±0.014（40毫安）和7.233±0.011（60毫安），并且在40毫安和60毫安时动脉血红蛋白分别增加34±3%和35±3%。在60毫安进行E-IM时，所有动脉血气和pH值的变化均显著大于40毫安时（P<0.05）。多元回归分析表明，E-IM期间动脉血氧分压的降低与呼吸延迟直接相关，而E-IM期间动脉血二氧化碳分压和pH值的变化并非如此。
