Kapoor Shailendra
Department of Family Medicine, University of Illinois at Chicago, Chicago, IL 60612, USA.
Skinmed. 2010 May-Jun;8(3):161-4; quiz 165.
Acanthosis nigricans is a dermatologic condition commonly seen in diabetics and obese individuals. Histologically, it is characterized by the proliferation of epidermal keratinocytes and fibroblasts. Clinically, the lesions appear as dark-brown thickened plaques. The neck and the axillas are the most commonly affected sites. Treatment involves management of the underlying disorder. Topical tretinoin and calcipotriol have also been used with some limited success. Other treatment options include laser and surgical excision.
黑棘皮病是一种常见于糖尿病患者和肥胖个体的皮肤病。从组织学上看，其特征是表皮角质形成细胞和成纤维细胞的增殖。临床上，病变表现为深褐色增厚斑块。颈部和腋窝是最常受累的部位。治疗包括对潜在疾病的管理。外用维甲酸和卡泊三醇也有一定的有限疗效。其他治疗选择包括激光和手术切除。
