Srinivasan G, Amin A, Pildes R S, Lilien L D, Matalon R
Department of Pediatrics, Cook County Children's Hospital, Chicago Medical School, Illinois 60612.
Indian J Pediatr. 1990 Jan-Feb;57(1):93-7. doi: 10.1007/BF02722138.
Plasma amino acids were measured in eight very low birth weight infants (less than or equal to 1000 gm) before and after infusion of parenteral alimentations with Freamine III. Significant elevation in serum threonine, valine, isoleucine, methionine, serine, proline, glycine and ornithine was noted after twenty four hours of infusion. On the other hand, significant decreases in taurine and tyrosine levels were noted. Our study suggests that current solution is not optimal for premature neonates and the amount of protein administered during the first week in infants weighing less than or equal to 1000 gm should be decreased from the recommended 2.5-3.0 gm/kg/day.
在八名极低出生体重儿（小于或等于1000克）输注含Freamine III的肠外营养前后测量了血浆氨基酸。输注24小时后，血清苏氨酸、缬氨酸、异亮氨酸、蛋氨酸、丝氨酸、脯氨酸、甘氨酸和鸟氨酸显著升高。另一方面，牛磺酸和酪氨酸水平显著下降。我们的研究表明，目前的溶液对早产儿并非最佳，对于体重小于或等于1000克的婴儿，第一周的蛋白质摄入量应从推荐的2.5 - 3.0克/千克/天减少。
