Akahori Hiroshi, Takeshita Yumie, Saito Reina, Kaneko Shuichi, Takamura Toshinari
Department of Disease Control and Homeostasis, Kanazawa University Graduate School of Medical Science.
Intern Med. 2010;49(23):2599-603. doi: 10.2169/internalmedicine.49.3978. Epub 2010 Dec 1.
Although the etiology of Graves' disease is still not clear, it is generally suggested that environmental factors such as infections contribute to the development of Graves' disease. We report here three cases of Graves' disease which presented simultaneously with infectious mononucleosis due to primary EBV infection. Acute EBV infection might play an important role in the onset of Graves' disease. These three women complained of a sore throat or neck pain, resembling subacute thyroiditis. In the case of thyrotoxicosis accompanied by sore throat or neck pain, Graves' disease must be distinguished from subacute thyroiditis.
尽管格雷夫斯病的病因仍不明确，但一般认为感染等环境因素会促使格雷夫斯病的发展。我们在此报告三例格雷夫斯病患者，她们同时因原发性EB病毒感染而患上传染性单核细胞增多症。急性EB病毒感染可能在格雷夫斯病的发病中起重要作用。这三名女性均主诉喉咙痛或颈部疼痛，类似亚急性甲状腺炎。对于伴有喉咙痛或颈部疼痛的甲状腺毒症病例，必须将格雷夫斯病与亚急性甲状腺炎区分开来。
