白内障手术及限钠引起的血压变化对视网膜血管直径的影响
Influence of cataract surgery and blood pressure changes caused by sodium restriction on retinal vascular diameter.
作者信息
Tano Takatoshi, Hiratsuka Yoshimune, Ono Koichi, Murakami Akira
机构信息
Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan.
出版信息
Clin Ophthalmol. 2010 Nov 15;4:1299-309. doi: 10.2147/OPTH.S14786.
PURPOSE
To investigate the impact of cataract surgery and blood pressure changes induced by one week of sodium restriction on retinal vascular diameter.
METHODS
Fundus photographs of 200 patients were obtained before and one week after cataract surgery. For one week after admission, 100 patients received sodium restriction and 100 patients (ie, the control group) did not receive sodium restriction. The diameter of the retinal vessels and blood pressure were compared between the sodium restriction group and the control group. The vascular diameter was measured using an objective computer-based method.
RESULTS
Neither group had a significant change in the diameter of the retinal vessels after cataract surgery. Although there was no significant change in retinal arterial and venular diameter in the sodium restriction group, one-week sodium restriction significantly reduced mean blood pressure. However, multiple linear regression analyses indicated that an increase in retinal arteriolar diameter was significantly associated with diabetes, hyperlipidemia, and alcohol intake.
CONCLUSION
Cataract surgery and blood pressure reduction induced by one week of sodium restriction resulted in no significant change in retinal arteriolar diameter.
目的
研究白内障手术及一周限钠引起的血压变化对视网膜血管直径的影响。
方法
获取200例患者白内障手术前及术后一周的眼底照片。入院后一周，100例患者接受限钠，100例患者（即对照组）未接受限钠。比较限钠组和对照组的视网膜血管直径及血压。使用基于计算机的客观方法测量血管直径。
结果
两组白内障手术后视网膜血管直径均无显著变化。尽管限钠组视网膜动脉和静脉直径无显著变化，但一周限钠显著降低了平均血压。然而，多元线性回归分析表明，视网膜小动脉直径增加与糖尿病、高脂血症和酒精摄入显著相关。
结论
白内障手术及一周限钠引起的血压降低并未导致视网膜小动脉直径发生显著变化。
Zotero 插件