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先天性巨大黑素细胞痣。

Congenital giant melanocytic nevi.

作者信息

Hashmi Ghulam S, Ahmed Syed S, Khan Shahla

机构信息

Dept. of Oral & Maxillofacial Surgery, Faculty of Medicine, Aligarh Muslim University, Aligarh, India;

出版信息

Rare Tumors. 2009 Jul 22;1(1):e9. doi: 10.4081/rt.2009.e9.

DOI:10.4081/rt.2009.e9
PMID:21139903
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2994429/
Abstract

Nevi are common skin tumors caused by abnormal overgrowth of cells from the epidermal and dermal layers of the skin. Most nevi are benign, but some pre-cancerous nevi must be monitored or removed. The giant congenital nevus is greater than 10 cm in size, pigmented and often hairy. Between 4% and 6% of these lesions will develop into a malignant melanoma. Since approximately 50% of the melanoma develop by the age of two, and 80% by the age of seven, early removal is recommended. The objective of this paper is to present a unique case of giant nevi and their surgical management.

摘要

痣是由皮肤表皮和真皮层细胞异常过度生长引起的常见皮肤肿瘤。大多数痣是良性的,但一些癌前痣必须进行监测或切除。巨大先天性痣大小超过10厘米,有色素沉着且通常有毛发。这些病变中有4%至6%会发展为恶性黑色素瘤。由于约50%的黑色素瘤在两岁前发病,80%在七岁前发病,因此建议尽早切除。本文的目的是介绍一例巨大痣的独特病例及其手术治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/252f/2994429/53a14fb5e461/rt-2009-1-e9-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/252f/2994429/6e689d606e1a/rt-2009-1-e9-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/252f/2994429/a59594ea95f2/rt-2009-1-e9-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/252f/2994429/bc5cef54a4cd/rt-2009-1-e9-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/252f/2994429/49023e01ce1f/rt-2009-1-e9-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/252f/2994429/ebd24d81ff39/rt-2009-1-e9-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/252f/2994429/53a14fb5e461/rt-2009-1-e9-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/252f/2994429/6e689d606e1a/rt-2009-1-e9-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/252f/2994429/a59594ea95f2/rt-2009-1-e9-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/252f/2994429/bc5cef54a4cd/rt-2009-1-e9-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/252f/2994429/49023e01ce1f/rt-2009-1-e9-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/252f/2994429/ebd24d81ff39/rt-2009-1-e9-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/252f/2994429/53a14fb5e461/rt-2009-1-e9-g006.jpg

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A large-scale collection of giant congenital melanocytic nevi: Clinical and histopathological characteristics.大量巨大先天性黑素细胞痣的收集:临床和组织病理学特征

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