Sakhiya Jagdish, Sakhiya Dhruv, Patel Mehul, Daruwala Feral
Department of Dermatology. Sakhiya Skin Clinic PVT LTD, Surat, Gujarat, India.
B.J. Medical College, New Civil Hospital Asarwa, Ahmedabad, Gujarat, India.
Indian Dermatol Online J. 2020 Jan 13;11(1):79-82. doi: 10.4103/idoj.IDOJ_107_19. eCollection 2020 Jan-Feb.
Congenital melanocytic nevi are benign proliferations of cutaneous melanocytes that arise as a result of abnormal growth, development, or migration of melanoblasts. Clinically, the giant congenital nevus is greater than 20 cm in size, pigmented and often hairy. The risk of malignant melanoma for the giant nevi is almost 6%. Fifty percent of the melanomas develop by the age of 2 years and, 80% of the melanomas develop by the age of 7 years. Hence, early management is of paramount importance. Herein, we present a case of giant nevi along with a review of the literature in order to bring awareness among clinicians towards this rare albeit significant entity.
先天性黑素细胞痣是皮肤黑素细胞的良性增殖，由成黑素细胞异常生长、发育或迁移所致。临床上，巨大先天性痣大小超过20 cm，有色素沉着且常多毛。巨大痣发生恶性黑色素瘤的风险近6%。50%的黑色素瘤在2岁前发生，80%在7岁前发生。因此，早期处理至关重要。在此，我们报告1例巨大痣病例并复习文献，以提高临床医生对这一罕见但重要疾病的认识。
