副肿瘤性眼阵挛-肌阵挛-共济失调综合征揭示双重恶性肿瘤。
Paraneoplastic opsoclonus-myoclonus-ataxia syndrome revealing dual malignancy.
作者信息
Nasri A, Kacem I, Jerdak F, Djebara M Ben, Mejri N, Sidhom Y, Gargouri A, Gouider Riadh
机构信息
Neurology department, Razi Hospital, UR 12SP21, Tunis, Tunisia.
Faculté de Médecine de Tunis, University of El Manar, Tunis, Tunisia.
出版信息
Neurol Sci. 2016 Oct;37(10):1723-5. doi: 10.1007/s10072-016-2632-8. Epub 2016 Jun 21.
Dual malignancy has been rarely associated to paraneoplastic syndromes. We describe an unusual case of metachronous small cell lung carcinoma revealed by opsoclonus-myoclonus ataxia syndrome in a 69-year-old patient with known prostate adenocarcinoma, with positive anti-Hu and anti-Yo antibodies and good responsiveness to corticosteroids and chemotherapy.
双原发恶性肿瘤很少与副肿瘤综合征相关。我们描述了一例罕见病例，一名69岁已知患有前列腺腺癌的患者，出现眼阵挛-肌阵挛性共济失调综合征，随后被诊断为异时性小细胞肺癌，其抗Hu和抗Yo抗体呈阳性，对皮质类固醇和化疗反应良好。
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