静脉注射胰蛋白酶后的实验性肺气肿
[Experimental emphysema following intravenous injection of trypsin].
作者信息
Reichart E, Plenat F, Boerkmann P, Vignaud J M
机构信息
Unité de Recherche, I.N.S.E.R.M. U. n. 14, Vandoeuvre-les-Nancy.
出版信息
C R Acad Sci III. 1990;310(13):619-24.
PMID:2114197
Abstract
The injection of trypsin provokes a decrease of the circulating antiproteases. Its effect on an elastase-induced emphysema is negligible. Paradoxically, emphysema is quantitatively demonstrated in rats treated with trypsin alone: an influx of polymorphonuclear leucocytes into the lung is observed during the acute phase of experiment.
摘要
注射胰蛋白酶会导致循环抗蛋白酶减少。其对弹性蛋白酶诱导的肺气肿的影响可忽略不计。矛盾的是，单独用胰蛋白酶处理的大鼠中可定量显示出肺气肿：在实验急性期观察到多形核白细胞流入肺部。
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