• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Differences in the effectiveness of EDTA to induce SCEs and chromosomal aberrations in CHO and Allium cepa chromosomes.

作者信息

Ortíz T, Cortés F

机构信息

Departamento de Biologia Celular, Facultad de Biologia, Universidad de Sevilla, Spain.

出版信息

Cytobios. 1990;61(246-247):187-93.

PMID:2114256
Abstract

The chelating agent EDTA was able to produce chromosome aberrations (CA) in CHO cells when it was administered simultaneously with BrdUrd (2 x 10(-5) M), without any concomitant effect on the yield of sister chromatid exchanges (SCEs). Root meristematic cells of Allium cepa did not show any type of CA when they were treated with different doses of EDTA (with or without BrdUrd 10(-4) M) while the SCE frequency was increased in a dose-dependent fashion. These effects of EDTA have not been previously reported. It is suggested that deprivation of divalent cations (Ca(+)+/Mg(+)+) probably play an important role in DNA replication and repair processes.

摘要

相似文献

1
Differences in the effectiveness of EDTA to induce SCEs and chromosomal aberrations in CHO and Allium cepa chromosomes.
Cytobios. 1990;61(246-247):187-93.
2
[Effect of 5-bromodeoxyuridine concentration on sister chromatid exchange frequency in consecutive replication cycles].[5-溴脱氧尿苷浓度对连续复制周期中姐妹染色单体交换频率的影响]
Genetika. 1983 Dec;19(12):1987-90.
3
Distribution of sister chromatid exchanges in chromosomes of normal Chinese hamster and its cell lines exposed to BrdU and MMC.正常中国仓鼠及其暴露于溴脱氧尿苷和丝裂霉素C的细胞系染色体中姐妹染色单体交换的分布
Cytobios. 1986;45(181):77-84.
4
Correlation of chromosomal aberrations and sister chromatid exchanges in individual CHO cells pre-labelled with BrdU and treated with DNaseI or X-rays.用BrdU预标记并经DNA酶I或X射线处理的单个中国仓鼠卵巢（CHO）细胞中染色体畸变与姐妹染色单体交换的相关性。
Int J Radiat Biol. 2002 Nov;78(11):1037-44. doi: 10.1080/09553000210166598.
5
Influence of inhibitors of poly(ADP-ribose) polymerase on DNA repair, chromosomal alterations, and mutations.聚（ADP - 核糖）聚合酶抑制剂对DNA修复、染色体改变及突变的影响。
Princess Takamatsu Symp. 1983;13:227-42.
6
Sister chromatid exchanges and chromosomal aberrations in Chinese hamster ovary (CHO-K1) cells treated with the insecticide pirimicarb.用杀虫剂嘧啶carb 处理的中国仓鼠卵巢（CHO-K1）细胞中的姐妹染色单体交换和染色体畸变。
J Hazard Mater. 2010 Feb 15;174(1-3):410-5. doi: 10.1016/j.jhazmat.2009.09.068. Epub 2009 Sep 20.
7
Chromosomal effects of sodium selenite in vivo. III. Aberrations and sister chromatid exchanges in Chinese hamster bone marrow.亚硒酸钠在体内的染色体效应。III. 中国仓鼠骨髓中的畸变和姐妹染色单体交换
Hereditas. 1980;93(1):101-5.
8
Factors affecting the production of SCEs by maleic hydrazide in root-tip chromosomes of Allium cepa.马来酰肼对洋葱根尖染色体姐妹染色单体交换产生影响的因素。
Mutat Res. 1987 Oct;192(2):125-30. doi: 10.1016/0165-7992(87)90108-4.
9
Cytogenetic effects of Me-CCNU on sister chromatid exchange frequency, cellular kinetics and chromosome aberrations.甲基环己亚硝脲对姐妹染色单体交换频率、细胞动力学及染色体畸变的细胞遗传学效应。
Neoplasma. 1986;33(1):33-7.
10
Cellular replication kinetics and persistence of sister chromatid exchange-inducing lesions in normal and lymphoma AKR cells following exposure to 1,3-bis(2-chloroethyl)-1-nitrosourea.正常和淋巴瘤AKR细胞暴露于1,3-双（2-氯乙基）-1-亚硝基脲后细胞复制动力学及诱导姐妹染色单体交换损伤的持续性
Cancer Res. 1982 Jul;42(7):2816-20.