Varghese Bipin Thomas, Mathew Aleyamma, Sebastian Paul, Iype Elizabeth Mathew, Vijay Archana
Division of Surgical Oncology, Regional Cancer Centre, Trivandrum, Kerala, India.
Acta Otolaryngol. 2011 Mar;131(3):310-5. doi: 10.3109/00016489.2010.526960. Epub 2010 Dec 10.
Quality of life (QOL) scores were significantly higher among voice rehabilitated patients although this was accompanied by significant immediate and long-term morbidity and a cost implication for the patient.
We present a prospective and cross-over study of overall QOL and morbidity related to voice restoration in laryngectomees.
The EORTC QOL questionnaire (QLQ-C30 and QLQ-H&N-35) was distributed among all the consenting patients alive after laryngectomy from January 2008 to October 2009. In patients who had secondary voice rehabilitation, post-rehabilitation QOL scores were collected separately. Comparison of QOL between the non-rehabilitated and rehabilitated cohorts was done and a cross-over study of pre-rehabilitation and post-rehabilitation scores were done in the second cohort.
A total of 113 patients were studied. QOL scores were significantly higher among voice rehabilitated patients.
尽管嗓音恢复的患者会出现显著的近期和长期发病率，并给患者带来经济负担，但他们的生活质量（QOL）得分显著更高。
我们对喉切除术后嗓音恢复相关的总体生活质量和发病率进行了一项前瞻性交叉研究。
2008年1月至2009年10月期间，将欧洲癌症研究与治疗组织（EORTC）生活质量问卷（QLQ-C30和QLQ-H&N-35）分发给所有接受喉切除术后存活且同意参与的患者。对于接受二次嗓音恢复的患者，分别收集恢复后的生活质量得分。对未恢复和恢复的队列进行生活质量比较，并对第二队列的恢复前和恢复后得分进行交叉研究。
共研究了113例患者。嗓音恢复的患者生活质量得分显著更高。
