Department of Oral Surgery, Faculty of Dentistry, University of Szeged, Tisza Lajos krt. 64, 6720, Szeged, Hungary.
Qual Life Res. 2014 Feb;23(1):135-43. doi: 10.1007/s11136-013-0446-1. Epub 2013 Jun 4.
The aim of the study was to evaluate patient-reported quality of life effects of post-treatment intraoral and extraoral rehabilitation in head and neck cancer by repeated measures.
Fifty-nine patients were involved. Basic socio-demographic, oncological and epidemiological data were gathered, and the type of rehabilitation was recorded. For the assessment of quality of life changes, two widely used brief questionnaires, the University of Washington Quality of Life Questionnaire and the Head and Neck module of the European Organization of Research and Treatment for Cancer Quality of Life Questionnaire, were used. The questionnaires were administered to patients two times: the first time after tumor therapy, but before rehabilitation (upon arriving for rehabilitation) and the second time 6 months after the application of any particular method of rehabilitation. Quality of life data were gathered prospectively, while socio-demographic data were gathered from patient files.
Quality of life after rehabilitation was significantly enhanced as compared to the post-treatment status, in all domains of both questionnaires (p < 0.05 and p < 0.01, Mann-Whitney U).
The results support the hypothesis that post-treatment maxillofacial rehabilitation in head and neck cancer does not only restore lost physical capabilities, but also brings about profound changes in patients' quality of life in general.
本研究旨在通过重复测量评估头颈部癌症治疗后口腔内和口腔外康复对患者报告的生活质量的影响。
共纳入 59 例患者。收集了基本的社会人口统计学、肿瘤学和流行病学数据，并记录了康复类型。为了评估生活质量的变化，使用了两个广泛使用的简短问卷，即华盛顿大学生活质量问卷和欧洲癌症研究与治疗组织生活质量问卷的头颈部模块。这些问卷分两次对患者进行评估：第一次是在肿瘤治疗后但在康复前（在进行康复时），第二次是在应用任何特定康复方法后 6 个月。生活质量数据是前瞻性收集的，而社会人口统计学数据则是从患者档案中收集的。
与治疗后状态相比，康复后所有问卷的所有领域的生活质量均显著提高（p<0.05 和 p<0.01，Mann-Whitney U）。
研究结果支持以下假设，即头颈部癌症治疗后的颌面康复不仅可以恢复丧失的身体功能，而且可以全面改善患者的生活质量。
