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基于深度学习流场的稳健羊膜镜拼接。

Robust fetoscopic mosaicking from deep learned flow fields.

机构信息

University of Bordeaux, Bordeaux, France.

Wellcome/EPSRC Centre for Interventional and Surgical Sciences (WEISS) and Department of Computer Science, University College London, London, UK.

出版信息

Int J Comput Assist Radiol Surg. 2022 Jun;17(6):1125-1134. doi: 10.1007/s11548-022-02623-1. Epub 2022 May 3.

DOI:10.1007/s11548-022-02623-1
PMID:35503395
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9124660/
Abstract

PURPOSE

Fetoscopic laser photocoagulation is a minimally invasive procedure to treat twin-to-twin transfusion syndrome during pregnancy by stopping irregular blood flow in the placenta. Building an image mosaic of the placenta and its network of vessels could assist surgeons to navigate in the challenging fetoscopic environment during the procedure.

METHODOLOGY

We propose a fetoscopic mosaicking approach by combining deep learning-based optical flow with robust estimation for filtering inconsistent motions that occurs due to floating particles and specularities. While the current state of the art for fetoscopic mosaicking relies on clearly visible vessels for registration, our approach overcomes this limitation by considering the motion of all consistent pixels within consecutive frames. We also overcome the challenges in applying off-the-shelf optical flow to fetoscopic mosaicking through the use of robust estimation and local refinement.

RESULTS

We compare our proposed method against the state-of-the-art vessel-based and optical flow-based image registration methods, and robust estimation alternatives. We also compare our proposed pipeline using different optical flow and robust estimation alternatives.

CONCLUSIONS

Through analysis of our results, we show that our method outperforms both the vessel-based state of the art and LK, noticeably when vessels are either poorly visible or too thin to be reliably identified. Our approach is thus able to build consistent placental vessel mosaics in challenging cases where currently available alternatives fail.

摘要

目的

羊膜镜激光光凝术是一种通过阻止胎盘内不规则血流来治疗妊娠期间双胎输血综合征的微创手术。构建胎盘及其血管网络的图像镶嵌图可以帮助外科医生在手术中导航具有挑战性的羊膜镜环境。

方法

我们提出了一种羊膜镜镶嵌方法,该方法将基于深度学习的光流与鲁棒估计相结合,以过滤由于浮动物体和镜面反射引起的不一致运动。虽然当前的羊膜镜镶嵌技术依赖于明显可见的血管进行注册,但我们的方法通过考虑连续帧中所有一致像素的运动克服了这一限制。我们还通过使用鲁棒估计和局部细化来克服将现成的光流应用于羊膜镜镶嵌的挑战。

结果

我们将我们提出的方法与基于血管的和基于光流的图像注册方法的最新技术以及鲁棒估计的替代方法进行了比较。我们还比较了我们使用不同光流和鲁棒估计替代方案的提出的管道。

结论

通过对结果的分析,我们表明我们的方法明显优于基于血管的最新技术和 LK,特别是当血管要么难以看到,要么太细而无法可靠识别时。因此,我们的方法能够在当前可用替代方案失败的情况下构建具有挑战性病例中的一致胎盘血管镶嵌图。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae52/9124660/61b7dfb4be0c/11548_2022_2623_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae52/9124660/1f9e45fced44/11548_2022_2623_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae52/9124660/39c1d2fcc144/11548_2022_2623_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae52/9124660/a7ea574c58a3/11548_2022_2623_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae52/9124660/5c29a4154e92/11548_2022_2623_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae52/9124660/61b7dfb4be0c/11548_2022_2623_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae52/9124660/1f9e45fced44/11548_2022_2623_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae52/9124660/39c1d2fcc144/11548_2022_2623_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae52/9124660/a7ea574c58a3/11548_2022_2623_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae52/9124660/5c29a4154e92/11548_2022_2623_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae52/9124660/61b7dfb4be0c/11548_2022_2623_Fig5_HTML.jpg

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本文引用的文献

1
Deep learning-based fetoscopic mosaicking for field-of-view expansion.基于深度学习的羊膜镜拼接技术,用于视野扩展。
Int J Comput Assist Radiol Surg. 2020 Nov;15(11):1807-1816. doi: 10.1007/s11548-020-02242-8. Epub 2020 Aug 17.
2
Retrieval and registration of long-range overlapping frames for scalable mosaicking of in vivo fetoscopy.用于体内胎儿镜可扩展拼接的远程重叠帧的检索和配准。
Int J Comput Assist Radiol Surg. 2018 May;13(5):713-720. doi: 10.1007/s11548-018-1728-4. Epub 2018 Mar 15.
3
Probabilistic visual and electromagnetic data fusion for robust drift-free sequential mosaicking: application to fetoscopy.
基于学习的胎儿镜拼接关键点配准。
Int J Comput Assist Radiol Surg. 2024 Mar;19(3):481-492. doi: 10.1007/s11548-023-03025-7. Epub 2023 Dec 9.
4
Toward a navigation framework for fetoscopy.胎儿镜检查的导航框架研究。
Int J Comput Assist Radiol Surg. 2023 Dec;18(12):2349-2356. doi: 10.1007/s11548-023-02974-3. Epub 2023 Aug 16.
用于稳健无漂移序列拼接的概率视觉与电磁数据融合:在胎儿镜检查中的应用
J Med Imaging (Bellingham). 2018 Apr;5(2):021217. doi: 10.1117/1.JMI.5.2.021217. Epub 2018 Feb 22.
4
Twin-to-twin transfusion syndrome (TTTS).双胎输血综合征(TTTS)。
J Perinat Med. 2011 Mar;39(2):107-12. doi: 10.1515/jpm.2010.147. Epub 2010 Dec 13.
5
Residual anastomoses after fetoscopic laser surgery in twin-to-twin transfusion syndrome: frequency, associated risks and outcome.双胎输血综合征胎儿镜激光手术后的残余吻合口:发生率、相关风险及结局
Placenta. 2007 Feb-Mar;28(2-3):204-8. doi: 10.1016/j.placenta.2006.03.005. Epub 2006 Apr 27.